A test for informative censoring in clustered survival data

被引:9
|
作者
Huang, XL [1 ]
Wolfe, RA
Hu, CC
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Biostat, Houston, TX 77030 USA
[2] Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA
[3] Harvard Univ, Dept Biostat, Boston, MA 02115 USA
关键词
correlation; dependent censoring; frailty model; martingale residual; positive stable distribution; survival analysis;
D O I
10.1002/sim.1801
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Frailty models a:re frequently used to analyse clustered survival data. The assumption of non-informative censoring is commonly used by these models, even though it may not be true in many situations. This article proposes a test for this assumption. It uses the estimated correlation between two types of martingale residuals, one from a model for failure and the other from a model for censoring. It distinguishes two types of censoring, namely withdrawal and the end of the study. Simulation studies show that the proposed test works Well under various scenarios. For illustration, the test is applied to a data set for kidney disease patients from multiple dialysis centres. Copyright (C) 2004 John Wiley Sons, Ltd.
引用
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页码:2089 / 2107
页数:19
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