Functional evaluation of variants of unknown significance in the homologous recombination genes BARD1 and BRCA2

被引:0
|
作者
Toh, M. [1 ]
Chan, S. [2 ]
Ishak, N. [2 ]
Chong, S. [2 ]
Ngeow, J. [1 ,2 ]
机构
[1] Duke NUS Med Sch, Singapore, Singapore
[2] Natl Canc Ctr, Singapore, Singapore
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
P12.029A
引用
收藏
页码:402 / 402
页数:1
相关论文
共 50 条
  • [21] Unraveling the mechanism of BRCA2 in homologous recombination
    Holloman, William K.
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2011, 18 (07) : 748 - 754
  • [22] Homologous recombination activity of BRCA2 VUS
    Guo, Qianqian
    Xu, Zeyu
    Saito, Hiroko
    Sunada, Shigeaki
    Miki, Yoshio
    CANCER SCIENCE, 2022, 113 : 365 - 365
  • [23] Functional analysis of clinical BARD1 germline variants
    Toh, Ming Ren
    Chong, Siao Ting
    Chan, Sock Hoai
    Low, Chen Ee
    Ishak, Nur Diana Binte
    Lim, Jing Quan
    Courtney, Eliza
    Ngeow, Joanne
    COLD SPRING HARBOR MOLECULAR CASE STUDIES, 2019, 5 (04):
  • [24] Functional assays for classification of BRCA2 variants of uncertain significance
    Farrugia, Daniel J.
    Agarwal, Mukesh K.
    Pankratz, Vernon S.
    Deffenbaugh, Amie M.
    Pruss, Dmitry
    Frye, Cynthia
    Wadum, Linda
    Johnson, Kiley
    Mentlick, Jennifer
    Tavtigian, Sean V.
    Goldgar, David E.
    Couch, Fergus J.
    CANCER RESEARCH, 2008, 68 (09) : 3523 - 3531
  • [25] Functional Assays for Analysis of Variants of Uncertain Significance in BRCA2
    Guidugli, Lucia
    Carreira, Aura
    Caputo, Sandrine M.
    Ehlen, Asa
    Galli, Alvaro
    Monteiro, Alvaro N. A.
    Neuhausen, Susan L.
    Hansen, Thomas V. O.
    Couch, Fergus J.
    Vreeswijk, Maaike P. G.
    HUMAN MUTATION, 2014, 35 (02) : 151 - 164
  • [26] The incidence of BRCA1 and BRCA2 variants of unknown significance varies in different ethnic populations.
    Opatt, D. M.
    Morrow, M.
    Daly, M.
    JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (18) : 541S - 541S
  • [27] Functional evaluation and clinical classification of BRCA2 variants
    Huang, Huaizhi
    Hu, Chunling
    Na, Jie
    Hart, Steven N.
    Gnanaolivu, Rohan David
    Abozaid, Mohamed
    Rao, Tara
    Tecleab, Yohannes A.
    CARRIERS Consortium, Christine B.
    Pesaran, Tina
    Lyra, Paulo Cilas Morais
    Karam, Rachid
    Yadav, Siddhartha
    Nathanson, Katherine L.
    Domchek, Susan M.
    de la Hoya, Miguel
    Robson, Mark
    Mehine, Miika
    Bandlamudi, Chaitanya
    Mandelker, Diana
    Monteiro, Alvaro N. A.
    Iversen, Edwin S.
    Boddicker, Nicholas
    Chen, Wenan
    Richardson, Marcy E.
    Couch, Fergus J.
    NATURE, 2025, : 528 - 537
  • [28] BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination
    Becker, Jordan R.
    Clifford, Gillian
    Bonnet, Clara
    Groth, Anja
    Wilson, Marcus D.
    Chapman, J. Ross
    NATURE, 2021, 596 (7872) : 433 - +
  • [29] Common Genetic Variation at BARD1 Is Not Associated with Breast Cancer Risk in BRCA1 or BRCA2 Mutation Carriers
    Spurdle, Amanda B.
    Marquart, Louise
    McGuffog, Lesley
    Healey, Sue
    Sinilnikova, Olga
    Wan, Fei
    Chen, Xiaoqing
    Beesley, Jonathan
    Singer, Christian F.
    Dressler, Anne-Catharine
    Gschwantler-Kaulich, Daphne
    Blum, Joanne L.
    Tung, Nadine
    Weitzel, Jeff
    Lynch, Henry
    Garber, Judy
    Easton, Douglas F.
    Peock, Susan
    Cook, Margaret
    Oliver, Clare T.
    Frost, Debra
    Conroy, Don
    Evans, D. Gareth
    Lalloo, Fiona
    Eeles, Ros
    Izatt, Louise
    Davidson, Rosemarie
    Chu, Carol
    Eccles, Diana
    Selkirk, Christina G.
    Daly, Mary
    Isaacs, Claudine
    Stoppa-Lyonnet, Dominique
    Buecher, Bruno
    Belotti, Muriel
    Mazoyer, Sylvie
    Barjhoux, Laure
    Verny-Pierre, Carole
    Lasset, Christine
    Dreyfus, Helene
    Pujol, Pascal
    Collonge-Rame, Marie-Agnes
    Rookus, Matti A.
    Verhoef, Senno
    Kriege, Mieke
    Hoogerbrugge, Nicoline
    Ausems, Margreet G. E. M.
    van Os, Theo A.
    Wijnen, Juul
    Devilee, Peter
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2011, 20 (05) : 1032 - 1038
  • [30] BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination
    Jordan R. Becker
    Gillian Clifford
    Clara Bonnet
    Anja Groth
    Marcus D. Wilson
    J. Ross Chapman
    Nature, 2021, 596 : 433 - 437