Role of in vitro testing in food allergy

被引：3

作者：

Arasi, Stefania ^{[1
]}

Barni, Simona ^{[2
]}

Mastrorilli, Carla ^{[3
]}

Comberiati, Pasquale ^{[4
]}

Chiera, Fernanda ^{[5
]}

Pelosi, Umberto ^{[6
]}

Paravati, Francesco ^{[5
]}

Caimmi, Davide ^{[7
,8
]}

机构：

[1] Bambino Gesu Childrens Res Hosp IRCCS, Dept Pediat Med, Pediat Allergol Unit, Rome, Italy

[2] Meyer Childrens Hosp, Dept Pediat, Allerg Unit, Florence, Italy

[3] Pediat Hosp Giovanni XXIII, Univ Hosp Consortium Corp Polyclin Bari, Dept Pediat, Bari, Italy

[4] Univ Pisa, Sect Pediat, Dept Clin & Expt Med, Pisa, Italy

[5] San Giovanni Dio Hosp, Dept Pediat, Crotone, Italy

[6] Santa Barbara Hosp, Pediat Unit, Iglesias, Italy

[7] Univ Montpellier, CHU Montpellier, Allergy Unit, Montpellier, France

[8] Sorbonne Univ, INSERM, UMR S 1136, Equipe EPAR,IPLESP, Paris, France

来源：

PEDIATRIC ALLERGY AND IMMUNOLOGY | 2020年 / 31卷

关键词：

basophil activation test; component resolved diagnostics; food allergy; IgE‐ mediated; IgG; specific IgE; EGG;

D O I：

10.1111/pai.13342

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Oral food challenges remain the gold standard for the diagnosis of food allergy. Nevertheless, the allergy workup is based on the presence of a clinical history, which is evocative of an immune-allergic reaction, and the first assessment is usually the performance of skin prick tests. Based on these results, allergists are used to evaluate the presence of serum-specific IgE, which are today the most commonly prescribed in vitro test for the evaluation of a possible food allergy. Other in vitro tests include the basophil activation test, that is becoming more and more employed by clinicians and not only by researchers, and the evaluation of serum IgG4, which is still an issue of debate in the allergy community. The present paper reviews the use of these in vitro tests for the diagnosis of food allergy.

引用

页码：36 / 38

页数：3

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