Rapid Determination of Pentazocine in Human Plasma and Urine by a Potentiometric Method

被引：9
|
作者：
Allafchian, Ali R. [1 ]
Ensafi, Ali A. [1 ]
Saraji, M. [1 ]
机构：
[1] Isfahan Univ Technol, Dept Chem, Esfahan 8415683111, Iran
来源：
ANALYTICAL LETTERS | 2009年 / 42卷 / 03期
关键词：
Coated wire; pentazocine; pharmaceutical samples; plasma; potentiometry; urine; LIQUID-MEMBRANE ELECTRODES; ION-SELECTIVE ELECTRODES; MASS-SPECTROMETRY; CHROMATOGRAPHY; SENSOR; HPLC;
D O I：
10.1080/00032710802677118
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A fast potentiometric determination method has been reported for pentazocine in human plasma without complicated pretreatments using a coated-wire potentiometric selective electrode. The sensing membrane was made by incorporating of ion-association complexes of pentazocine cation and sodium tetraphenyl borate (NaTPB) in a polyvinyl chloride. The sensor exhibited fast, stable, and linear Nernstian response over the range of 510-5 to 0.1molL-1 pentazocine with a slope of 57.8mV per decade and with detection limit of 3.210-5molL-1. The proposed sensor has been used for determination of pentazocine in human plasma and urine.
引用
收藏
页码：571 / 583
页数：13
相关论文
共 50 条
12345