Synthesis, Characterization and Molecular Docking Studies of 4-(5-Alkylsulfanyl-(1,3,4)oxadiazol-2-yl methyl)-7-methyl chromene-2-ones

被引：0
|
作者：
Gaddam, Ganga Reddy [1 ]
Sudugu, Ramakrishna Reddy [1 ]
Chittireddy, Venkata Ramana Reddy [1 ]
Bireddy, Srinivasa Reddy [2 ]
Eppakayala, Laxminarayana [3 ]
机构：
[1] Jawaharlal Nehru Technol Univ Hyderabad, Dept Chem, Hyderabad, Telangana, India
[2] Mahatma Gandhi Inst Technol, Dept Chem, Hyderabad, Telangana, India
[3] Sreenidhi Inst Sci & Technol Autonomous Yamnampet, Dept Chem, Hyderabad, Telangana, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2022年 / 32卷 / 04期
关键词：
DERIVATIVES; 1,3,4-OXADIAZOLES;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of 4-(5-alkylsulfanyl-[1,3,4]oxadiazol-2-ylmethyl)-7-methyl-chromen-2-ones (5a-d) was synthesized from (7-methyl-2-oxo-2H-chromen-4-yl)-acetic acid (1) as starting material. The structures of the synthesized new compounds were confirmed by their H-1-NMR, IR, and mass spectral data. The molecular docking studies of the compounds have been carried out to predict the possible anti-depressant activity.
引用
收藏
页码：449 / 453
页数：5
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