Synthesis, Characterization and Molecular Docking Studies of 4-(5-Alkylsulfanyl-(1,3,4)oxadiazol-2-yl methyl)-7-methyl chromene-2-ones

被引：0

作者：

Gaddam, Ganga Reddy ^{[1
]}

Sudugu, Ramakrishna Reddy ^{[1
]}

Chittireddy, Venkata Ramana Reddy ^{[1
]}

Bireddy, Srinivasa Reddy ^{[2
]}

Eppakayala, Laxminarayana ^{[3
]}

机构：

[1] Jawaharlal Nehru Technol Univ Hyderabad, Dept Chem, Hyderabad, Telangana, India

[2] Mahatma Gandhi Inst Technol, Dept Chem, Hyderabad, Telangana, India

[3] Sreenidhi Inst Sci & Technol Autonomous Yamnampet, Dept Chem, Hyderabad, Telangana, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2022年 / 32卷 / 04期

关键词：

DERIVATIVES; 1,3,4-OXADIAZOLES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 4-(5-alkylsulfanyl-[1,3,4]oxadiazol-2-ylmethyl)-7-methyl-chromen-2-ones (5a-d) was synthesized from (7-methyl-2-oxo-2H-chromen-4-yl)-acetic acid (1) as starting material. The structures of the synthesized new compounds were confirmed by their H-1-NMR, IR, and mass spectral data. The molecular docking studies of the compounds have been carried out to predict the possible anti-depressant activity.

引用

页码：449 / 453

页数：5

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