Ribosome-associated protein quality control

被引：309

作者：

Brandman, Onn ^{[1
]}

Hegde, Ramanujan S. ^{[2
]}

机构：

[1] Stanford Univ, Dept Biochem, Stanford, CA 94305 USA

[2] MRC, Mol Biol Lab, Cambridge CB2 2QH, England

来源：

NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2016年 / 23卷 / 01期

基金：

美国国家卫生研究院; 英国医学研究理事会;

关键词：

MESSENGER-RNA DECAY; DEPENDENT TRANSLATION ARREST; E3 UBIQUITIN LIGASE; CONTROL COMPLEX; COTRANSLATIONAL UBIQUITINATION; SUBUNIT DISSOCIATION; STRUCTURAL BASIS; NASCENT CHAINS; POLY(A) TAIL; DEGRADATION;

D O I：

10.1038/nsmb.3147

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Protein synthesis by the ribosome can fail for numerous reasons including faulty mRNA, insufficient availability of charged tRNAs and genetic errors. All organisms have evolved mechanisms to recognize stalled ribosomes and initiate pathways for recycling, quality control and stress signaling. Here we review the discovery and molecular dissection of the eukaryotic ribosome-associated quality-control pathway for degradation of nascent polypeptides arising from interrupted translation.

引用

页码：7 / 15

页数：9

共 50 条

[21] Ribosome-associated quality control of membrane proteins at the endoplasmic reticulum
Phillips, Ben P.
Miller, Elizabeth A.
JOURNAL OF CELL SCIENCE, 2020, 133 (22)
[22] Unveiling the Nexus of Cellular Quality Control: Exploring the Interplay between Ribosome-Associated Protein Quality Control and Mitochondrial Quality Control Pathways
Tahmasebinia, Foozhan
Tang, Yinglu
Tang, Rushi
Zhang, Yi
Chen, Songjie
Snyder, Michael
Liu, Boxiang
Wu, Zhihao
JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 300 (03) : S515 - S515
[23] G-protein control of the ribosome-associated stress response protein SpoT
Jiang, Mengxi
Sullivan, Susan M.
Wout, Patrice K.
Maddock, Janine R.
JOURNAL OF BACTERIOLOGY, 2007, 189 (17) : 6140 - 6147
[24] Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP
Crowe-McAuliffe, Caillan
Takada, Hiraku
Murina, Victoriia
Polte, Christine
Kasvandik, Sergo
Tenson, Tanel
Ignatova, Zoya
Atkinson, Gemma C.
Wilson, Daniel N.
Hauryliuk, Vasili
MOLECULAR CELL, 2021, 81 (01) : 115 - +
[25] Ribosome-associated quality-control mechanisms from bacteria to humans
Filbeck, Sebastian
Cerullo, Federico
Pfeffer, Stefan
Joazeiro, Claudio A. P.
MOLECULAR CELL, 2022, 82 (08) : 1451 - 1466
[26] Alanine Tails Signal Proteolysis in Bacterial Ribosome-Associated Quality Control
Lytvynenko, Iryna
Paternoga, Helge
Thrun, Anna
Balke, Annika
Mueller, Tina A.
Chiang, Christina H.
Nagler, Katja
Tsaprailis, George
Anders, Simon
Bischofs, Ilka
Maupin-Furlow, Julie A.
Spahn, Christian M. T.
Joazeiro, Claudio A. P.
CELL, 2019, 178 (01) : 76 - +
[27] Transcriptional profile of ribosome-associated quality control components and their associated phenotypes in mammalian cells
Otávio Augusto Leitão Dos Santos
Rodolfo L. Carneiro
Rodrigo D. Requião
Marcelo Ribeiro-Alves
Tatiana Domitrovic
Fernando L. Palhano
Scientific Reports, 14
[28] Transcriptional profile of ribosome-associated quality control components and their associated phenotypes in mammalian cells
Dos Santos, Otavio Augusto Leitao
Carneiro, Rodolfo L.
Requiao, Rodrigo D.
Ribeiro-Alves, Marcelo
Domitrovic, Tatiana
Palhano, Fernando L.
SCIENTIFIC REPORTS, 2024, 14 (01)
[29] Detection and Degradation of Stalled Nascent Chains via Ribosome-Associated Quality Control
Sitron, Cole S.
Brandman, Onn
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 89, 2020, 89 : 417 - 442
[30] Ribosome-associated quality control (RQC) in Saccharomyces cerevisiae upon oxidative stress
Pietrzyk, M.
Chacinska, A.
FEBS OPEN BIO, 2018, 8 : 484 - 484

← 1 2 3 4 5 →