A Convenient Synthesis of Pyrazole-imidazoline Derivatives by Microwave Irradiation

被引：10
|
作者：
Rosa, Getulio de S. [1 ]
Souto, Bernardo A. [1 ]
Pereira, Cynthia N. [1 ]
Teixeira, Bruna C. [1 ]
dos Santos, Mauricio S. [1 ]
机构：
[1] Univ Fed Itajuba, Inst Fis & Quim, Lab Sintese Organ LABSINTO, 1303 BPS Ave, BR-37500903 Itajuba, MG, Brazil
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2019年 / 56卷 / 06期
关键词：
BIOLOGICAL-ACTIVITIES; 2-IMIDAZOLINES; ANALOGS; DESIGN;
D O I：
10.1002/jhet.3557
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of 28 hybrids pyrazole-imidazolines 1a-n and 2a-n were synthesized by a new methodology using microwave irradiation, in short time (20-30min), in low power (50-70W), and in 34-92% yield. Among all methodologies evaluated, no side products were obtained. All derivatives were completely characterized by FT-IR, H-1 and C-13 NMR, GC-MS, and HRMS.
引用
收藏
页码：1825 / 1830
页数：6
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