IL-1 gene polymorphism and periodontal status of HIV Brazilians on highly active antiretroviral therapy

被引：3
|
作者：
Goncalves, Lucio de S. [1 ]
Ferreira, Sonia Maria S.
Souza, Celso O.
Colombo, Ana Paula V.
机构：
[1] Univ Fed Rio de Janeiro, Inst Microbiol, Rio De Janeiro, Brazil
[2] Univ Fed Rio de Janeiro, Sch Dent, Rio De Janeiro, Brazil
来源：
AIDS | 2006年 / 20卷 / 13期
关键词：
D O I：
10.1097/01.aids.0000242826.97495.7c
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A genotype in the IL-1 gene cluster is associated with an increased risk of periodontitis. We investigated whether polymorphisms in the IL-1A +4845 and IL-1B +3954 loci affect the periodontal status of HIV-infected Brazilians on HAART. HIV-positive and HIV-negative subjects with periodontitis were genotyped for IL-1 by polymerase chain reaction and restriction enzyme digestion. Only 11.4% of patients were genotype positive. No associations between genotype positivity and HIV infection or periodontal status were found in this population.
引用
收藏
页码：1779 / 1781
页数：3
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