IL-1 gene polymorphism and periodontal status of HIV Brazilians on highly active antiretroviral therapy

被引：3
|
作者：
Goncalves, Lucio de S. [1 ]
Ferreira, Sonia Maria S.
Souza, Celso O.
Colombo, Ana Paula V.
机构：
[1] Univ Fed Rio de Janeiro, Inst Microbiol, Rio De Janeiro, Brazil
[2] Univ Fed Rio de Janeiro, Sch Dent, Rio De Janeiro, Brazil
来源：
AIDS | 2006年 / 20卷 / 13期
关键词：
D O I：
10.1097/01.aids.0000242826.97495.7c
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A genotype in the IL-1 gene cluster is associated with an increased risk of periodontitis. We investigated whether polymorphisms in the IL-1A +4845 and IL-1B +3954 loci affect the periodontal status of HIV-infected Brazilians on HAART. HIV-positive and HIV-negative subjects with periodontitis were genotyped for IL-1 by polymerase chain reaction and restriction enzyme digestion. Only 11.4% of patients were genotype positive. No associations between genotype positivity and HIV infection or periodontal status were found in this population.
引用
收藏
页码：1779 / 1781
页数：3
相关论文
共 50 条
  • [1] Alleles of the gene encoding IL-1α may predict control of plasma viraemia in HIV-1 patients on highly active antiretroviral therapy
    Price, P
    James, L
    Fernandez, S
    French, MA
    [J]. AIDS, 2004, 18 (11) : 1495 - 1501
  • [2] HIV infections and nutritional status during highly active antiretroviral therapy
    Spacone, A
    Ricci, F
    Falasca, K
    Ceccomancini, A
    Dalessandro, M
    Pizzigallo, E
    [J]. TWELFTH NATIONAL CONVENTION: AIDS AND RELATED SYNDROMES, 2000, : 171 - 174
  • [3] Vitamin D Status in Children Living with HIV on Highly Active Antiretroviral Therapy
    Aquino A.
    Collier J.
    Arathoon E.
    [J]. Current Tropical Medicine Reports, 2017, 4 (3) : 158 - 165
  • [4] Highly active antiretroviral therapy and HIV transmission
    Montaner, Julio
    [J]. LANCET, 2006, 368 (9548): : 1647 - 1647
  • [5] Clinical and microbiological profiles of human immunodeficiency virus (HIV)-seropositive Brazilians undergoing highly active antiretroviral therapy and HIV-seronegative Brazilians with chronic periodontitis
    Goncalves, Lucio de Souza
    Soares Ferreira, Sonia Maria
    Souza, Celso Oliveira
    Souto, Renata
    Colombo, Ana Paula
    [J]. JOURNAL OF PERIODONTOLOGY, 2007, 78 (01) : 87 - 96
  • [6] Mast Cells in Periodontal Disease of Individuals With and Without HIV Undergoing Highly Active Antiretroviral Therapy
    Segundo, Takeshi Kato
    Souto, Giovanna Ribeiro
    Costa, Fernando Oliveira
    Mesquita, Ricardo Alves
    [J]. JOURNAL OF PERIODONTOLOGY, 2013, 84 (07) : 995 - 1001
  • [7] Langerhans cells in periodontal disease of HIV- and HIV plus patients undergoing highly active antiretroviral therapy
    Segundo, Takeshi Kato
    Sauto, Giovanna Ribeiro
    Mesquita, Ricardo Alves
    Costa, Fernando Oliveira
    [J]. BRAZILIAN ORAL RESEARCH, 2011, 25 (03): : 255 - 260
  • [8] Clinical treatment outcomes of periodontal therapy in HIV-seropositive patients undergoing highly active antiretroviral therapy
    Jordan, A. R.
    Gaengler, P.
    Joehren, H. -P.
    [J]. EUROPEAN JOURNAL OF MEDICAL RESEARCH, 2006, 11 (06) : 232 - 235
  • [9] IL-1β+3953 polymorphism X chronic periodontal disease
    Trevilatto, PC
    Scarel, RM
    Souza, AP
    Brito, RBJ
    Line, SP
    [J]. JOURNAL OF DENTAL RESEARCH, 2002, 81 : B43 - B43
  • [10] HIV transmission under highly active antiretroviral therapy
    Vernazza, Pietro
    Hirschel, Bernard
    Bernasconi, Enos
    Flepp, Markus
    [J]. LANCET, 2008, 372 (9652): : 1806 - 1807
12345