Understanding the significance variables for fabrication of fish gelatin nanoparticles by Plackett-Burman design

被引：3

作者：

Subara, Deni ^{[1
]}

Jaswir, Irwandi ^{[1
,2
]}

Alkhatib, Maan Fahmi Rashid ^{[1
]}

Noorbatcha, Ibrahim Ali ^{[1
]}

机构：

[1] Int Islamic Univ Malaysia, Fac Engn, Dept Biotechnol Engn, Kuala Lumpur 53100, Malaysia

[2] Int Islamic Univ Malaysia, Int Inst Halal Res & Training INHART, Kuala Lumpur, Malaysia

来源：

INTERNATIONAL CONFERENCE ON ADVANCES IN MANUFACTURING AND MATERIALS ENGINEERING (ICAMME 2017) | 2018年 / 290卷

关键词：

ALBUMIN NANOPARTICLES; 2-STEP DESOLVATION; AMPHOTERICIN-B; DRUG; OPTIMIZATION; DELIVERY; EFFICIENCY; SIZE;

D O I：

10.1088/1757-899X/290/1/012006

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The aim of this experiment is to screen and to understand the process variables on the fabrication of fish gelatin nanoparticles by using quality-design approach. The most influencing process variables were screened by using Plackett-Burman design. Mean particles size, size distribution, and zeta potential were found in the range 240 +/- 9.76 nm, 0.3, and -9 mV, respectively. Statistical results explained that concentration of acetone, pH of solution during precipitation step and volume of cross linker had a most significant effect on particles size of fish gelatin nanoparticles. It was found that, time and chemical consuming is lower than previous research. This study revealed the potential of quality-by design in understanding the effects of process variables on the fish gelatin nanoparticles production.

引用

页数：6

共 50 条

[21] Insights into the effect of preparation variables on morphology and performance of polyacrylonitrile membranes using Plackett-Burman design experiments
Wang, Pan
Wang, Zhiwei
Wu, Zhichao
CHEMICAL ENGINEERING JOURNAL, 2012, 193 : 50 - 58
[22] Choosing columns from the 12-run Plackett-Burman design
Miller, A
Sitter, RR
STATISTICS & PROBABILITY LETTERS, 2004, 67 (02) : 193 - 201
[23] Improving the capillary electrophoretic analysis of poliovirus using a Plackett-Burman design
Oita, Iuliana
Halewyck, Hadewych
Pieters, Sigrid
Dejaegher, Bieke
Thys, Bert
Rombaut, Bart
Heyden, Yvan Vander
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2009, 50 (04) : 655 - 663
[24] SCREENING OF PROBIOTIC GOAT MILK TABLETS USING PLACKETT-BURMAN DESIGN
Chen, He
Zhang, Jianhua
Shu, Guowei
ACTA SCIENTIARUM POLONORUM-TECHNOLOGIA ALIMENTARIA, 2014, 13 (04) : 351 - 358
[25] Assessment of Liquid Chromatographic Method Robustness by Use of Plackett-Burman Design
Maskovic, M.
Jancic-Stojanovic, B.
Malenovic, A.
Ivanovic, D.
Medenica, M.
ACTA CHROMATOGRAPHICA, 2010, 22 (02) : 281 - 296
[26] EVALUATION OF COATED PAPER QUALITY USING A PLACKETT-BURMAN STATISTICAL DESIGN
Tyagi, Sanjay
Ray, A. K.
CELLULOSE CHEMISTRY AND TECHNOLOGY, 2010, 44 (09): : 407 - 414
[27] HIGH-YIELD SULFITE PULPING BASED ON A PLACKETT-BURMAN DESIGN
BRODERICK, G
VALADE, JL
PARIS, J
PULP & PAPER-CANADA, 1993, 94 (09) : 22 - 25
[28] The Generalization of Plackett-Burman Design Based on Fractional Calculus of Complex Order
Ibrahim, Rabha W.
Jalab, Hamid A.
INTERNATIONAL CONFERENCE ON QUANTITATIVE SCIENCES AND ITS APPLICATIONS (ICOQSIA 2014), 2014, 1635 : 107 - 112
[29] ANALYSIS OF WET GRANULATION PROCESS WITH PLACKETT-BURMAN DESIGN - CASE STUDY
Woyna-Orlewicz, Krzysztof
Jachowicz, Renata
ACTA POLONIAE PHARMACEUTICA, 2011, 68 (05): : 725 - 733
[30] Development of paclitaxel and flurbiprofen co-loaded PLGA nanoparticles: understanding critical formulation and process parameters using Plackett-Burman design
Sahin, Adem
Caban-Toktas, Secil
Tonbul, Hayrettin
Yerlikaya, Firat
Aktas, Yesim
Capan, Yilmaz
ISTANBUL JOURNAL OF PHARMACY, 2019, 49 (03): : 161 - 166

← 1 2 3 4 5 →