Palladium-Catalysed Direct Arylation using Free-Amine-Substituted Polyfluoroanilines with Inhibition of Amination-Type Reaction

被引：4

作者：

Takfaoui, Abdelilah ^{[1
,2
,3
]}

Touzani, Rachid ^{[2
,3
]}

Soule, Jean-Francois ^{[1
]}

Dixneuf, Pierre H. ^{[1
]}

Doucet, Henri ^{[1
]}

机构：

[1] Univ Rennes 1, Inst Sci Chim Rennes, UMR CNRS 6226, Organometall Mat & Catalyse, F-35042 Rennes, France

[2] Univ Mohamed Premier, Fac Sci, LCAE URAC18, Oujda, Morocco

[3] Univ Mohamed Premier, Fac Pluridisciplinaire Nador, Selouane 62700, Nador, Morocco

来源：

ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 4卷 / 10期

关键词：

amination; catalysis; C-H bond functionalization; polyfluoroarenes; palladium; C-H ARYLATION; ELECTRON-DEFICIENT POLYFLUOROARENES; INTERMOLECULAR DIRECT ARYLATION; CROSS-COUPLING REACTIONS; ARYL; FUNCTIONALIZATION; MECHANISM; PHOSPHINES; METALATION; SYSTEM;

D O I：

10.1002/ajoc.201500268

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium-catalysed C-C bond formation via direct arylation of free-amine-substituted polyfluoroaniline derivatives proceeds in moderate to high yields with a variety of aryl bromides. The nature of the base was found to be crucial to promote the direct arylation with inhibition of the amination reaction.

引用

页码：1085 / 1095

页数：11

共 24 条

[21] A new type of palladium-catalysed aromatic cross-coupling combined with a Suzuki reaction:: synthesis of selectively 2,3′-substituted 1,1′;2′,1"-terphenyl derivatives
Motti, E
Mignozzi, A
Catellani, M
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2003, 204 : 115 - 124
[22] Di(1H-benzo[d][1,2,3]triazol-1-yl)methane: An efficient ligand for copper and amine-free palladium-catalysed Sonogashira coupling reaction
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JOURNAL OF CHEMICAL SCIENCES, 2011, 123 (06) : 937 - 942
[23] Di(1H-benzo[d][1,2,3]triazol-1-yl)methane: An efficient ligand for copper and amine-free palladium-catalysed Sonogashira coupling reaction
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Journal of Chemical Sciences, 2011, 123 (6) : 937 - 942
[24] Palladium-acetate catalyst for regioselective direct arylation at C2 of 3-furanyl or 3-thiophenyl acrylates with inhibition of Heck type reaction
Chen, Lu
Bruneau, Christian
Dixneuf, Pierre H.
Doucet, Henri
TETRAHEDRON, 2013, 69 (22) : 4381 - 4388

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