Palladium-Catalysed Direct Arylation using Free-Amine-Substituted Polyfluoroanilines with Inhibition of Amination-Type Reaction

被引：4
|
作者：
Takfaoui, Abdelilah [1 ,2 ,3 ]
Touzani, Rachid [2 ,3 ]
Soule, Jean-Francois [1 ]
Dixneuf, Pierre H. [1 ]
Doucet, Henri [1 ]
机构：
[1] Univ Rennes 1, Inst Sci Chim Rennes, UMR CNRS 6226, Organometall Mat & Catalyse, F-35042 Rennes, France
[2] Univ Mohamed Premier, Fac Sci, LCAE URAC18, Oujda, Morocco
[3] Univ Mohamed Premier, Fac Pluridisciplinaire Nador, Selouane 62700, Nador, Morocco
来源：
ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 4卷 / 10期
关键词：
amination; catalysis; C-H bond functionalization; polyfluoroarenes; palladium; C-H ARYLATION; ELECTRON-DEFICIENT POLYFLUOROARENES; INTERMOLECULAR DIRECT ARYLATION; CROSS-COUPLING REACTIONS; ARYL; FUNCTIONALIZATION; MECHANISM; PHOSPHINES; METALATION; SYSTEM;
D O I：
10.1002/ajoc.201500268
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The palladium-catalysed C-C bond formation via direct arylation of free-amine-substituted polyfluoroaniline derivatives proceeds in moderate to high yields with a variety of aryl bromides. The nature of the base was found to be crucial to promote the direct arylation with inhibition of the amination reaction.
引用
收藏
页码：1085 / 1095
页数：11
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