After more than 50 years of operation of the research reactor operated by UJV Rez, a. s. (UJV) or the Research Centre Ref, as the case may be, a large amount of spent nuclear fuel (SNF) of Russian origin has accumulated. In 2005, UJV joined the Russian Research Reactor Fuel Return (RRRFR) program under the US-Russian Global Threat Reduction Initiative (GTRI) and started the process of SNF shipment from the LVR-15 research reactor back to the Russian Federation (RF) using the SKODA VPVR/M transport packaging system (TPS). Two SNF shipments from UJV were carried out in 2007 and 2013. After the shipments were completed, only low-enriched nuclear fuel with a maximum enrichment below 20% of U-235 remained on the territory of the Czech Republic. UJV also participates in, shipments of SNF from other countries. The services of UJV comprise mainly SKODA VPVR/M TPS leasing, technical oversight and expertise during cask handling, SNF loading and cask closing and sealing. Up to now, UJV has participated in thirteen shipments of SNF from eight countries; one shipment is currently being prepared. High-level radioactive waste (HLW) will be generated from SNF reprocessing. The vitrified HLW will be returned to the Czech Republic as stated in the Russian-Czech Intergovernmental Agreement on Co-operation in Nuclear Energy. The return of the waste represents very complex and complicated work, technically, legally and contractually.