IL-1β Exacerbates Amyloid Deposition In Islets: A Mechanism for Increased β-Cell Loss in Type 2 Diabetes?

被引:0
|
作者
Mellati, Mahnaz
Meier, Daniel
Hogan, Meghan F.
Templin, Andrew T.
Kahn, Steven E.
机构
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2092-P
引用
收藏
页码:A535 / A535
页数:1
相关论文
共 50 条
  • [21] β-Cell Loss and β-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition (vol 178, pg 2632, 2011)
    Jurgens, C. A.
    AMERICAN JOURNAL OF PATHOLOGY, 2011, 179 (01): : 537 - 538
  • [22] The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: A novel mechanism of regulation of IL-1 responsiveness
    Lang, D
    Knop, J
    Wesche, H
    Raffetseder, U
    Kurrle, R
    Boraschi, D
    Martin, MU
    JOURNAL OF IMMUNOLOGY, 1998, 161 (12): : 6871 - 6877
  • [23] Interleukin-1 (IL-1) family of cytokines: Role in Type 2 Diabetes
    Banerjee, Monisha
    Saxena, Madhukar
    CLINICA CHIMICA ACTA, 2012, 413 (15-16) : 1163 - 1170
  • [24] Is IL-1 the Bridge Connecting Type 2 Diabetes and Cardiac Arrhythmias? COMMENT
    Stoll, Lisa
    Lo, James C.
    JACC-BASIC TO TRANSLATIONAL SCIENCE, 2021, 6 (01): : 53 - 54
  • [25] Loss of immune tolerance to IL-2 in type 1 diabetes
    Louis Pérol
    John M. Lindner
    Pamela Caudana
    Nicolas Gonzalo Nunez
    Audrey Baeyens
    Andrea Valle
    Christine Sedlik
    Delphine Loirat
    Olivier Boyer
    Alain Créange
    José Laurent Cohen
    Ute Christine Rogner
    Jun Yamanouchi
    Martine Marchant
    Xavier Charles Leber
    Meike Scharenberg
    Marie-Claude Gagnerault
    Roberto Mallone
    Manuela Battaglia
    Pere Santamaria
    Agnès Hartemann
    Elisabetta Traggiai
    Eliane Piaggio
    Nature Communications, 7
  • [26] Loss of immune tolerance to IL-2 in type 1 diabetes
    Perol, Louis
    Lindner, John M.
    Caudana, Pamela
    Nunez, Nicolas Gonzalo
    Baeyens, Audrey
    Valle, Andrea
    Sedlik, Christine
    Loirat, Delphine
    Boyer, Olivier
    Creange, Alain
    Cohen, Jose Laurent
    Rogner, Ute Christine
    Yamanouchi, Jun
    Marchant, Martine
    Leber, Xavier Charles
    Scharenberg, Meike
    Gagnerault, Marie-Claude
    Mallone, Roberto
    Battaglia, Manuela
    Santamaria, Pere
    Hartemann, Agnes
    Traggiai, Elisabetta
    Piaggio, Eliane
    NATURE COMMUNICATIONS, 2016, 7
  • [27] Blocking IL-1 Receptor Reduces Amyloid Formation and Enhances Beta-Cell Survival and Function in Cultured Human Islets
    Park, Yoo Jin
    Maedler, Kathrin
    Ao, Ziliang
    Safikhan, Nooshin
    Warnock, Garth L.
    Marzban, Lucy
    DIABETES, 2013, 62 : A556 - A556
  • [28] Associations between interleukin-1 (IL-1) gene variations or IL-1 receptor antagonist levels and the development of type 2 diabetes
    Luotola, K.
    Pietila, A.
    Zeller, T.
    Moilanen, L.
    Kahonen, M.
    Nieminen, M. S.
    Kesaniemi, Y. A.
    Blankenberg, S.
    Jula, A.
    Perola, M.
    Salomaa, V.
    JOURNAL OF INTERNAL MEDICINE, 2011, 269 (03) : 322 - 332
  • [29] IL-1beta expression in human islets is induced by glucose and autostimulation, and increased in beta cells of individuals with type 2 diabetes
    Boeni-Schnetzler, M.
    Marselli, L.
    Parnaud, G.
    Ehses, J. A.
    Halban, P. A.
    Weir, G. C.
    Donath, M. Y.
    DIABETOLOGIA, 2007, 50 : S178 - S178
  • [30] Loss of T follicular regulatory cell-derived IL-1R2 augments germinal center reactions via increased IL-1
    Pyrillou, Katerina
    Humphry, Melanie
    Kitt, Lauren A.
    Rodgers, Amanda
    Nus, Meritxell
    Bennett, Martin R.
    Smith, Kenneth G. C.
    Lyons, Paul A.
    Mallat, Ziad
    Clarke, Murray C. H.
    JCI INSIGHT, 2024, 9 (05)