Non-invasive Lesion Imaging and Delivery of Nano-Therapeutics to the Ischemic Brain

被引：0
|
作者：
Choi, Angela O. [1 ]
Vaisheva, Farida [1 ]
Soliman, Ghareb M. [1 ]
Maysinger, Dusica [1 ]
机构：
[1] McGill Univ, Fac Med, Dept Pharmacol & Therapeut, 3655 Promenade Sir William Osler, Montreal, PQ, Canada
来源：
NANOTECHNOLOGY 2011: BIO SENSORS, INSTRUMENTS, MEDICAL, ENVIRONMENT AND ENERGY, NSTI-NANOTECH 2011, VOL 3 | 2011年
基金：
加拿大自然科学与工程研究理事会;
关键词：
ischemic stroke; inflammation; quantum dot; minocycline; nimodipine; STROKE; MINOCYCLINE; NIMODIPINE; COCKTAIL; PENUMBRA; INJURY; CELLS;
D O I：
暂无
中图分类号：
TE [石油、天然气工业]; TK [能源与动力工程];
学科分类号：
0807 ; 0820 ;
摘要：
Ischemic brain microlesions are often asymptomatic, but can cause irreversible neurodegenerative damage if they remain undetected and untreated. Inflammatory processes, involving activated microglia, are triggered at and around ischemic lesion sites. Early detection of microlesions using fluorescent nanocrystals (quantum dots), together with therapeutic interventions, utilizing anti-inflammatory agents, may provide an effective nano-theranostic approach for ischemic stroke therapy.
引用
收藏
页码：467 / 470
页数：4
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