Physical Positioning Dramatically Improves Brain Transduction after Intrathecal Infusion of AAV9

被引：0
|
作者：
Castle, Michael J. [1 ]
Cheng, Yuhsiang [1 ]
Asokan, Aravind [2 ,3 ]
Tuszynski, Mark H. [1 ]
机构：
[1] Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
[2] Duke Univ, Sch Med, Dept Surg, Durham, NC USA
[3] Duke Univ, Sch Med, Dept Mol Genet & Microbiol, Durham, NC USA
来源：
MOLECULAR THERAPY | 2019年 / 27卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
187
引用
收藏
页码：97 / 98
页数：2
相关论文
共 50 条
  • [21] Enteric Nervous System Transduction Following Intravascular Delivery of AAV9
    Lampe, S. E. Gombash
    Cowley, C. J.
    Christofi, F. L.
    Fitzgerald, J. A.
    Foust, K. D.
    MOLECULAR THERAPY, 2014, 22 : S91 - S91
  • [22] Axonal transport of AAV9 in nonhuman primate brain
    F Green
    L Samaranch
    H S Zhang
    A Manning-Bog
    K Meyer
    J Forsayeth
    K S Bankiewicz
    Gene Therapy, 2016, 23 : 520 - 526
  • [23] Enhanced Cochlear Transduction by AAV9 with High-Concentration Sucrose
    Noda, Masao
    Koshu, Ryota
    Dias, Mari Shimada
    Saito, Chizu
    Takino, Naomi
    Ito, Mika
    Yoshimura, Hidekane
    Ito, Makoto
    Muramatsu, Shin-ichi
    HUMAN GENE THERAPY, 2023, 34 (19-20) : 1064 - 1071
  • [24] Pretreatment with IVIG Reduces Peripheral Transduction of AAV9 Delivered to the CNS
    West, Cara
    Mastis, Bryan
    Vandenberghe, Luk H.
    Richman, Laura K.
    Calcedo, Roberto
    MOLECULAR THERAPY, 2022, 30 (04) : 21 - 21
  • [25] Axonal transport of AAV9 in nonhuman primate brain
    Green, F.
    Samaranch, L.
    Zhang, H. S.
    Manning-Bog, A.
    Meyer, K.
    Forsayeth, J.
    Bankiewicz, K. S.
    GENE THERAPY, 2016, 23 (06) : 520 - 526
  • [26] Biodistribution of adeno-associated virus serotype 9 (AAV9) vector after intrathecal and intravenous delivery in mouse
    Schuster, Daniel J.
    Dykstra, Jaclyn A.
    Riedl, Maureen S.
    Kitto, Kelley F.
    Belur, Lalitha R.
    McIvor, R. Scott
    Elde, Robert P.
    Fairbanks, Carolyn A.
    Vulchanova, Lucy
    FRONTIERS IN NEUROANATOMY, 2014, 8
  • [27] Strong Cortical and Spinal Cord Transduction After AAV7 and AAV9 Delivery into the Cerebrospinal Fluid of Nonhuman Primates
    Samaranch, Lluis
    Salegio, Ernesto A.
    Sebastian, Waldy San
    Kells, Adrian P.
    Bringas, John R.
    Forsayeth, John
    Bankiewicz, Krystof S.
    HUMAN GENE THERAPY, 2013, 24 (05) : 526 - 532
  • [28] Improved AAV9 Transduction of the Central Nervous System and Retina After Co-Treatment with Neuraminidase
    Schwartz, Maura
    Huffenberger, Amy
    Pineda, Ricardo
    Baird, Megan
    Likhite, Shibi
    Meyer, Kathrin
    MOLECULAR THERAPY, 2020, 28 (04) : 92 - 92
  • [29] Customized Blood-Brain Barrier Shuttle Peptide to Increase AAV9 Vector Crossing the BBB and Enhance Transduction in the Brain
    Zhang, Xintao
    Chai, Zheng
    Dobbins, Amanda Lee
    Samulski, Richard Jude
    Li, Chengwen
    MOLECULAR THERAPY, 2019, 27 (04) : 186 - 186
  • [30] AAV9 Capsid Variants with Improved CNS Transduction Identified by Directed Evolution
    Rohovie, Marcus
    Kruse, Nikki
    Schmitt, Christopher
    Wong, Victoria
    Sero, Antoinette
    Rivera-Velazquez, Mirella
    Lee, Grace
    Desautel, Sarah
    Del Greco, Elizabeth
    Sedighi, Faezeh
    Nivina, Aleksandra
    Jenne, Stephan
    Gebretsadik, Kahsay
    Kumar, Ambuj
    Chng, Chinping
    Akeefe, Hassibullah
    Silverman, Adam
    MOLECULAR THERAPY, 2023, 31 (04) : 661 - 661
12345