Can we predict flu-like symptoms in patients with multiple sclerosis treated with interferon-β?

被引：7
|
作者：
Montalban, X [1 ]
Durán, I [1 ]
Río, J [1 ]
Sáez-Torres, I [1 ]
Tintoré, M [1 ]
Martínez-Cáceres, EM [1 ]
机构：
[1] Hosp Gen Univ Valle Hebron, Serv Neurol, Unitat Neuroimmunol Clin, Barcelona, Spain
来源：
JOURNAL OF NEUROLOGY | 2000年 / 247卷 / 04期
关键词：
multiple sclerosis; flu-like symptoms; interferon-beta(1b); interleukin-6;
D O I：
10.1007/s004150050580
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Interferon-beta(1b) treatment in relapsing-remitting multiple sclerosis can frequently induce systemic side effects such as flu-like symptoms with fever. In vitro stimulation of peripheral blood leukocytes with interferon-beta(1b) before the beginning of therapy shows that patients who develop fever generally have increased levels of interleukin-6.
引用
收藏
页码：259 / 262
页数：4
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