Can we predict flu-like symptoms in patients with multiple sclerosis treated with interferon-β?

被引：7

作者：

Montalban, X ^{[1
]}

Durán, I ^{[1
]}

Río, J ^{[1
]}

Sáez-Torres, I ^{[1
]}

Tintoré, M ^{[1
]}

Martínez-Cáceres, EM ^{[1
]}

机构：

[1] Hosp Gen Univ Valle Hebron, Serv Neurol, Unitat Neuroimmunol Clin, Barcelona, Spain

来源：

JOURNAL OF NEUROLOGY | 2000年 / 247卷 / 04期

关键词：

multiple sclerosis; flu-like symptoms; interferon-beta(1b); interleukin-6;

D O I：

10.1007/s004150050580

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Interferon-beta(1b) treatment in relapsing-remitting multiple sclerosis can frequently induce systemic side effects such as flu-like symptoms with fever. In vitro stimulation of peripheral blood leukocytes with interferon-beta(1b) before the beginning of therapy shows that patients who develop fever generally have increased levels of interleukin-6.

引用

页码：259 / 262

页数：4

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