Due to the complex climate types and various meteorological disasters in gansu province, with the background of climate change dominated by warming, the losses caused by meteorological disasters are increasing. The understanding of disaster risk characteristics and its response to climate change need to be solved urgently. In view of this, this study based on the data of the disaster situation of major meteorological stations in gansu province since 1961, constructed the disaster risk index - comprehensive loss rate, and systematically analyzed the space-time variation characteristics of drought, rainstorm and flood, wind and hail and low temperature disasters in gansu province, and discussed the impact of climate change on them. The results show that since 1961, the risk of agricultural drought disaster is the greatest, followed by wind hail and rainstorm flood, and the risk of cold disaster is relatively minimal. Among them, drought disaster, disaster and loss rate (25.2%, 14.1% and 2.2%) were significantly higher than the national average (15.0%, 8.1% and 1.7%), and the increase rate (0.16%/10a, 0.15%/10a and 0.05%/10a) was also higher than the national average. The comprehensive loss rates of storm hails, rainstorm and flood disasters and cold and cold disasters also showed an increasing trend, with the increase rates of 0.29%/10a, 0.45%/10 and 0.72%/10a, respectively. The characteristics of inter- decadal disaster risk change have obvious differences, and the drought disaster risk increases uniformly. After climate change, the risk of major meteorological disasters in gansu increased.