Protein recognition and denaturation by self-assembling fragments on a DNA quadruplex scaffold

被引：44

作者：

Tagore, Debarati M. ^{[1
]}

Sprinz, K. Ingrid ^{[1
]}

Fletcher, Steven ^{[1
]}

Jayawickramarajah, Janarthanan ^{[1
]}

Hamilton, Andrew D. ^{[1
]}

机构：

[1] Yale Univ, Dept Chem, New Haven, CT 06520 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 1-2期

关键词：

DNA structures; enzymes; self-assembly; supramolecular chemistry; surface recognition;

D O I：

10.1002/anie.200603479

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Recognize this face? Quadruplex DNA has been used as a noncovalent scaffold to project binding groups for protein recognition and denaturation, with the best quadruplex decreasing the melting temperature of cytochrome c by about 45 K. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：223 / 225

页数：3

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