Biomedical applications of holographic microspectroscopy [Invited]

被引：32

作者：

Jung, JaeHwang ^{[1
]}

Kim, Kyoohyun ^{[1
]}

Yu, HyeonSeung ^{[1
]}

Lee, KyeoReh ^{[1
]}

Lee, SeoEun ^{[2
]}

Nahm, SeungHoon ^{[3
]}

Park, HyunJoo ^{[1
]}

Park, YongKeun ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Phys, Taejon 305701, South Korea

[2] Korea Adv Inst Sci & Technol, Dept Biol Sci, Taejon 305701, South Korea

[3] Korea Res Inst Stand & Sci, Ctr Energy Mat Metrol, Taejon 305340, South Korea

来源：

APPLIED OPTICS | 2014年 / 53卷 / 27期

基金：

新加坡国家研究基金会;

关键词：

OPTICAL COHERENCE TOMOGRAPHY; SPECTROSCOPIC PHASE MICROSCOPY; TRANSFORM LIGHT-SCATTERING; QUANTITATIVE PHASE; REFRACTIVE-INDEX; DIFFRACTION PHASE; MOLECULAR CONTRAST; HEMOGLOBIN CONCENTRATION; IMAGING TECHNIQUES; CELL;

D O I：

10.1364/AO.53.00G111

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

The identification and quantification of specific molecules are crucial for studying the pathophysiology of cells, tissues, and organs as well as diagnosis and treatment of diseases. Recent advances in holographic microspectroscopy, based on quantitative phase imaging or optical coherence tomography techniques, show promise for label-free noninvasive optical detection and quantification of specific molecules in living cells and tissues (e.g., hemoglobin protein). To provide important insight into the potential employment of holographic spectroscopy techniques in biological research and for related practical applications, we review the principles of holographic microspectroscopy techniques and highlight recent studies. (C) 2014 Optical Society of America

引用

页码：G111 / G122

页数：12

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