Unfaithful association of FCGR2B genetic polymorphisms with susceptibility to SLE

被引:1
|
作者
Napolioni, Valerio [1 ]
Barucca, Alessandra [1 ]
Bolli, Elisabetta [1 ]
Concetti, Antonio [1 ]
Venanzi, Franco Maria [1 ]
机构
[1] Univ Camerino, Dept Biol MCA, I-62032 Camerino, Italy
关键词
Single nucleotide polymorphisms; FCGR2B; FCGR2C; homology; systemic lupus erythematosus; SYSTEMIC-LUPUS-ERYTHEMATOSUS; GAMMA-RECEPTOR-IIB; CHINESE POPULATIONS; EXPRESSION; HAPLOTYPE;
D O I
10.1080/08916930802438782
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Correcting errors and proofreading are crucial in a post-genomic era, when DNA sequences are already part of an effective medical screening and treatments. SNPs genotyping of complex human genes can lead to questionable associations if not properly handled. Here, we report about a spurious (reitered) association between FCGR2B genetic polymorphisms and systemic lupus erythematosus.
引用
收藏
页码:139 / 142
页数:4
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