Towards a total synthesis of guanacastepene A: construction of fully functionalized AB and BC ring segments

被引:32
|
作者
Mehta, G [1 ]
Umarye, JD [1 ]
Gagliardini, V [1 ]
机构
[1] Indian Inst Sci, Dept Organ Chem, Bangalore 560012, Karnataka, India
关键词
D O I
10.1016/S0040-4039(02)01597-6
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Studies directed towards the total synthesis of the diterpene antibiotic, guanacastepene A, of current interest and displaying promising biological activity against drug-resistant pathogens, has led to the acquisition of fully functionalized AB and BC ring segments of the natural product. (C) 2002 Published by Elsevier Science Ltd.
引用
收藏
页码:6975 / 6978
页数:4
相关论文
共 50 条
  • [31] Stereoselective synthesis of the fully functionalized GHIJ ring fragment of gambieric acids
    Maroto, Sergio
    Evans, P. Andrew
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
  • [32] Asymmetric synthesis of the fully functionalized six-membered ring of trigoxyphin A
    Feng, Jing
    Yu, Tianzi
    Zhang, Zhijiang
    Li, Jinpeng
    Fu, Shaomin
    Chen, Juan
    Liu, Bo
    CHEMICAL COMMUNICATIONS, 2018, 54 (55) : 7665 - 7668
  • [33] Studies Towards the Total Synthesis of Populusone: Stereoselective Construction of Functionalized 2-Oxa-bicyclo[2.2.2]octenes
    Hemmersbach, Lars
    Schmalz, Hans-Guenther
    SYNLETT, 2023, 34 (03) : 238 - 242
  • [34] AN ASYMMETRIC-SYNTHESIS OF FULLY FUNCTIONALIZED B-RING-SYSTEM OF TAXOL
    SHIINA, I
    UOTO, K
    MORI, N
    KOSUGI, T
    MUKAIYAMA, T
    CHEMISTRY LETTERS, 1995, (03) : 181 - 182
  • [35] Asymmetric synthesis of the fully functionalized six-membered A-ring of siphonol A
    Sun, Ying
    Fu, Shaomin
    Liu, Bo
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 22 (15) : 2958 - 2962
  • [36] Convergent synthesis of fully functionalized ring C allocolchicinoids. Benzannulation approach
    Vorogushin, AV
    Wulff, WD
    Hansen, HJ
    ORGANIC LETTERS, 2001, 3 (17) : 2641 - 2644
  • [37] Alternative synthesis and thermal atropisomerism of a fully functionalized DEFG ring system of teicoplanin
    Mori, Y
    McAtee, JJ
    Rogel, O
    Boger, DL
    TETRAHEDRON LETTERS, 2001, 42 (35) : 6061 - 6064
  • [38] STUDIES ON THE TOTAL SYNTHESIS OF SESBANIMIDE - A HIGHLY DIASTEREOSELECTIVE SYNTHESIS OF THE AB RING-SYSTEM
    ROUSH, WR
    MICHAELIDES, MR
    TETRAHEDRON LETTERS, 1986, 27 (29) : 3353 - 3356
  • [39] Construction of Iterative Tetrahydrofuran Ring Units and Total Synthesis of (+)-Goniocin
    Suzuki, Ai
    Sasaki, Mai
    Nakagishi, Tetsuya
    Ueda, Tsuyoshi
    Hoshiya, Naoyuki
    Uenishi, Jun'ichi
    ORGANIC LETTERS, 2016, 18 (09) : 2248 - 2251
  • [40] A CONVERGENT STRATEGY TOWARDS TAXOL - A FACILE ENANTIOSELECTIVE ENTRY INTO A FULLY FUNCTIONALIZED RING ALPHA SYSTEM
    NICOLAOU, KC
    HWANG, CK
    SORENSEN, EJ
    CLAIRBORNE, CF
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1992, (16) : 1117 - 1118