Towards a total synthesis of guanacastepene A: construction of fully functionalized AB and BC ring segments

被引：32
|
作者：
Mehta, G [1 ]
Umarye, JD [1 ]
Gagliardini, V [1 ]
机构：
[1] Indian Inst Sci, Dept Organ Chem, Bangalore 560012, Karnataka, India
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 39期
关键词：
D O I：
10.1016/S0040-4039(02)01597-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Studies directed towards the total synthesis of the diterpene antibiotic, guanacastepene A, of current interest and displaying promising biological activity against drug-resistant pathogens, has led to the acquisition of fully functionalized AB and BC ring segments of the natural product. (C) 2002 Published by Elsevier Science Ltd.
引用
收藏
页码：6975 / 6978
页数：4
相关论文
共 50 条
  • [1] Towards the Total Synthesis of Gedunin: Construction of the Fully Elaborated ABC Ring System
    Pinkerton, David M.
    Bernhardt, Paul V.
    Savage, G. Paul
    Williams, Craig M.
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2017, 6 (05) : 583 - 597
  • [2] Diastereoselective Total Synthesis of (±)-Schindilactone A, Part 2: Construction of the Fully Functionalized CDEFGH Ring System
    Li, Yong
    Chen, Zhi-Xing
    Xiao, Qing
    Ye, Qin-Da
    Sun, Tian-Wen
    Meng, Fan-Ke
    Ren, Wei-Wu
    You, Lin
    Xu, Ling-Min
    Wang, Yue-Fan
    Chen, Jia-Hua
    Yang, Zhen
    CHEMISTRY-AN ASIAN JOURNAL, 2012, 7 (10) : 2334 - 2340
  • [3] ORGN 910-Studies towards the total synthesis of guanacastepene A
    Greaney, Michael F.
    McGowan, Craig A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232
  • [4] Synthetic studies toward the zoanthamine alkaloids: synthesis of the fully functionalized BC ring motif
    Rivas, F
    Ghosh, S
    Theodorakis, EA
    TETRAHEDRON LETTERS, 2005, 46 (32) : 5281 - 5284
  • [5] Asymmetric Total Synthesis of Propindilactone G, Part 2: Enantioselective Construction of the Fully Functionalized BCDE Ring System
    Zhang, Jia-Jun
    You, Lin
    Wang, Yue-Fan
    Li, Yuan-He
    Liang, Xin-Ting
    Zhang, Bo
    Yang, Shou-Liang
    Su, Qi
    Chen, Jia-Hua
    Yang, Zhen
    CHEMISTRY-AN ASIAN JOURNAL, 2016, 11 (09) : 1414 - 1424
  • [6] Remarkable stereoselectivity in the alkylation of a hydroazulenone: progress towards the total synthesis of guanacastepene
    Dudley, GB
    Tan, DS
    Kim, G
    Tanski, JM
    Danishefsky, SJ
    TETRAHEDRON LETTERS, 2001, 42 (39) : 6789 - 6791
  • [7] Studies toward the total synthesis of diterpene antibiotic guanacastepene A: Construction of the hydroazulenic core
    Mehta, G
    Umarye, JD
    ORGANIC LETTERS, 2002, 4 (07) : 1063 - 1066
  • [8] Studies toward the total synthesis of eletefine: an efficient construction of the AB ring system
    Cody, Jeremy A.
    Ahmed, Ijaz
    Tusch, Douglas J.
    TETRAHEDRON LETTERS, 2010, 51 (42) : 5585 - 5587
  • [9] Total synthesis of siomycin A: Construction of synthetic segments
    Mori, Tomonori
    Higashibayashi, Shuhei
    Goto, Taiji
    Kohno, Mitsunori
    Satouchi, Yukiko
    Shinko, Kazuyuki
    Suzuki, Kengo
    Suzuki, Shunya
    Tohmiya, Hiraku
    Hashimoto, Kimiko
    Nakata, Masaya
    CHEMISTRY-AN ASIAN JOURNAL, 2008, 3 (06) : 984 - 1012
  • [10] Synthesis of a highly functionalized tricyclic ring system related to guanacastepene via a tandem ring-closing metathesis reaction
    Boyer, FD
    Hanna, I
    TETRAHEDRON LETTERS, 2002, 43 (42) : 7469 - 7472
12345