A new class of estrogen receptor-α (ERα) inhibitors to treat tamoxifen-resistant breast cancers

被引:0
|
作者
Singh, Kriti [1 ]
Munuganti, Ravi S. N. [1 ]
Butler, Miriam [1 ]
Leblanc, Eric [1 ]
Cherkasov, Artem [1 ]
Rennie, Paul S. [1 ]
机构
[1] Univ British Columbia, Vancouver Prostate Ctr, Vancouver, BC V6H 3Z6, Canada
关键词
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
158
引用
收藏
页码:S19 / S19
页数:1
相关论文
共 50 条
  • [1] Tamoxifen-resistant breast cancers show less frequent methylation of the estrogen receptor β but not the estrogen receptor α gene
    Ho Gun Chang
    Sun Jung Kim
    Ki-Wook Chung
    Dong-Young Noh
    Youngmee Kwon
    Eun Sook Lee
    Han-Sung Kang
    [J]. Journal of Molecular Medicine, 2005, 83 : 132 - 139
  • [2] Tamoxifen-resistant breast cancers show less frequent methylation of the estrogen receptor β but not the estrogen receptor αgene
    Chang, HG
    Kim, SJ
    Chung, KW
    Noh, DY
    Kwon, Y
    Lee, ES
    Kang, HS
    [J]. JOURNAL OF MOLECULAR MEDICINE-JMM, 2005, 83 (02): : 132 - 139
  • [3] ESTROGEN-RECEPTOR MUTATIONS IN TAMOXIFEN-RESISTANT BREAST-CANCER
    KARNIK, PS
    KULKARNI, S
    LIU, XP
    BUDD, GT
    BUKOWSKI, RM
    [J]. CANCER RESEARCH, 1994, 54 (02) : 349 - 353
  • [4] Development of new estrogen receptor-targeting therapeutic agents for tamoxifen-resistant breast cancer
    Jiang, Quan
    Zheng, Shilong
    Wang, Guangdi
    [J]. FUTURE MEDICINAL CHEMISTRY, 2013, 5 (09) : 1023 - 1035
  • [5] Selective human estrogen receptor partial agonist (ShERPAs) for treatment of tamoxifen-resistant ER plus breast cancer
    Delgado-Rivera, Loruhama M.
    [J]. CANCER RESEARCH, 2016, 76
  • [6] Characterization of new estrogen receptor destabilizing compounds:: Effects on estrogen-sensitive and tamoxifen-resistant breast cancer
    Hoffmann, J
    Bohlmann, R
    Heinrich, N
    Hofmeister, H
    Kroll, J
    Künzer, H
    Lichtner, RB
    Nishino, Y
    Parczyk, K
    Sauer, G
    Gieschen, H
    Ulbrich, HF
    Schneider, MR
    [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2004, 96 (03) : 210 - 218
  • [7] Increased expression of estrogen receptor β mRNA in tamoxifen-resistant breast cancer patients
    Speirs, V
    Malone, C
    Walton, DS
    Kerin, MJ
    Atkin, SL
    [J]. CANCER RESEARCH, 1999, 59 (21) : 5421 - 5424
  • [8] ZIRA: A new prognostic biomarker of estrogen receptor- positive (ER plus ) breast cancers
    Vendrell, J.
    Nguyen, N. T.
    Gyorffy, B.
    Leon, S.
    Grisard, E.
    Bachelot, T.
    Treilleux, I.
    Cohen, P. A.
    [J]. EUROPEAN JOURNAL OF CANCER, 2014, 50 : S155 - S155
  • [9] In-silico discovery of novel estrogen receptor-α inhibitors as potential therapeutics for tamoxifen resistant breast cancer
    Singh, Kriti
    Munuganti, Ravi S. N.
    Butler, Miriam
    Cherkasov, Artem
    Rennie, Paul S.
    [J]. CANCER RESEARCH, 2015, 75
  • [10] Selective Human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer
    Xiong, Rui
    Patel, Hitisha K.
    Gutgesell, Lauren M.
    Zhao, Jiong
    Delgado-Rivera, Loruhama
    Pham, Thao N. D.
    Zhao, Huiping
    Carlson, Kathryn
    Martin, Teresa
    Katzenellenbogen, John A.
    Moore, Terry W.
    Tonetti, Debra A.
    Thatcher, Gregory R. J.
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2016, 59 (01) : 219 - 237