Microbial conversion of glycerol to 1,3-propanediol: Recent progress

The microbial conversion of glycerol to 1,3-propanediol has recently received much attention because of the appealing properties of 1,3-propanediol and the anticipated surplus of glycerol on the market. Our knowledge of the metabolic pathway, the intrinsic metabolic potential and kinetic limitation of this bioconversion process has been substantially augmented. Progress has also been made in improving the process performance and strains both on process engineering and molecular biology levels. These recent advances are summarized in this communication. Further research and development needs are also discussed.