The genetic jigsaw of inflammatory bowel disease

被引:0
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作者
Watts, DA [1 ]
Satsangi, J [1 ]
机构
[1] Univ Edinburgh, Western Gen Hosp, Gastrointestinal Unit, Edinburgh EH4 2XU, Midlothian, Scotland
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R57 [消化系及腹部疾病];
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摘要
Following a prolonged period of relative inertia, real progress has been made in the past few years in understanding the pathogenesis of the chronic inflammatory bowel diseases, Crohn's disease and ulcerative colitis. Clinical experience, epidemiological studies, and molecular genetics have provided strong evidence that both genetic and environmental factors are important in disease pathogenesis, and gene-environmental interaction determines disease susceptibility and behaviour.
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页码:31 / 36
页数:6
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