CSF1R+PD-L1+ TUMOR-ASSOCIATED MACROPHAGES TRIGGER MAIT CELL DYSFUNCTION AT THE HCC INVASIVE MARGIN

被引：0

作者：

Ruf, Benjamin ^{[1
]}

Bruhns, Matthias ^{[2
]}

Babaei, Sepideh ^{[2
]}

Kedei, Noemi ^{[1
]}

Ma, Chi ^{[1
]}

Ma, Lichun ^{[1
]}

Revsine, Mahler ^{[1
]}

Heinrich, Bernd ^{[1
]}

Subramanyam, Varun ^{[1
]}

Qi, Jonathan ^{[1
]}

Wabitsch, Simon ^{[1
]}

Green, Benjamin ^{[1
]}

Bauer, Kylynda ^{[1
]}

Myojin, Yuta ^{[1
]}

Benmebarek, Mohamed-Reda ^{[1
]}

Greten, Layla ^{[1
]}

McCallen, Justin ^{[1
]}

Huang, Patrick ^{[1
]}

Pouzolles, Marie ^{[1
]}

Kleiner, David ^{[1
]}

Telford, William ^{[1
]}

Dadkhah, Kimia ^{[1
]}

Ruchinskas, Allison ^{[1
]}

Stoffroff, Merrill ^{[1
]}

Kang, Jiman ^{[3
]}

Oza, Kesha ^{[3
]}

Ruchirawat, Mathuros ^{[4
]}

Kroemer, Alexander ^{[3
]}

Wang, Xin ^{[1
]}

Claassen, Manfred

Korangy, Firouzeh ^{[1
]}

Greten, Tim ^{[1
]}

机构：

[1] NIH, Bethesda, MD USA

[2] Univ Hosp Tubingen, Tubingen, Germany

[3] MedStar Georgetown Univ Hosp, Washington, DC USA

[4] Chulabhorn Res Inst, Bangkok, Thailand

来源：

JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2022年 / 10卷

关键词：

D O I：

10.1136/jitc-2022-SITC2022.1019

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

1019

引用

页码：A1062 / A1062

页数：1

共 50 条

[41] GM-CSF derived from the inflammatory microenvironment potentially enhanced PD-L1 expression on tumor-associated macrophages in human breast cancer
Yonemitsu, Kimihiro
Pan, Cheng
Fujiwara, Yukio
Miyasato, Yuko
Shiota, Takuya
Yano, Hiromu
Hosaka, Seiji
Tamada, Koji
Yamamoto, Yutaka
Komohara, Yoshihiro
SCIENTIFIC REPORTS, 2022, 12 (01)
[42] GM-CSF derived from the inflammatory microenvironment potentially enhanced PD-L1 expression on tumor-associated macrophages in human breast cancer
Kimihiro Yonemitsu
Cheng Pan
Yukio Fujiwara
Yuko Miyasato
Takuya Shiota
Hiromu Yano
Seiji Hosaka
Koji Tamada
Yutaka Yamamoto
Yoshihiro Komohara
Scientific Reports, 12
[43] Targeted systemic dendrimer delivery of CSF-1R inhibitor to tumor-associated macrophages improves outcomes in orthotopic glioblastoma
Liaw, Kevin
Reddy, Rajsekhar
Sharma, Anjali
Li, Jiangyu
Chang, Michelle
Sharma, Rishi
Salazar, Sebastian
Kannan, Sujatha
Kannan, Rangaramanujam M.
BIOENGINEERING & TRANSLATIONAL MEDICINE, 2021, 6 (02)
[44] CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model
I-Li Tan
Raquel Duque Nascimento Arifa
Harikrishna Rallapalli
Veronika Kana
Zhimin Lao
Reeti Mayur Sanghrajka
N. Sumru Bayin
Antoine Tanne
Alexandre Wojcinski
Andrey Korshunov
Nina Bhardwaj
Miriam Merad
Daniel H. Turnbull
Juan J. Lafaille
Alexandra L. Joyner
Oncogene, 2021, 40 : 396 - 407
[45] CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model
Tan, I-Li
Arifa, Raquel Duque Nascimento
Rallapalli, Harikrishna
Kana, Veronika
Lao, Zhimin
Sanghrajka, Reeti Mayur
Sumru Bayin, N.
Tanne, Antoine
Wojcinski, Alexandre
Korshunov, Andrey
Bhardwaj, Nina
Merad, Miriam
Turnbull, Daniel H.
Lafaille, Juan J.
Joyner, Alexandra L.
ONCOGENE, 2021, 40 (02) : 396 - 407
[46] Regulation of PD-L1 expression on murine tumor-associated monocytes and macrophages by locally produced TNF-α
Genevieve Hartley
Daniel Regan
Amanda Guth
Steven Dow
Cancer Immunology, Immunotherapy, 2017, 66 : 523 - 535
[47] Regulation of PD-L1 expression on murine tumor-associated monocytes and macrophages by locally produced TNF-α
Hartley, Genevieve
Regan, Daniel
Guth, Amanda
Dow, Steven
CANCER IMMUNOLOGY IMMUNOTHERAPY, 2017, 66 (04) : 523 - 535
[48] Biomimetic "Gemini nanoimmunoregulators" orchestrated for boosted photoimmunotherapy by spatiotemporally modulating PD-L1 and tumor-associated macrophages
Huang, Honglin
Li, Ningxi
Wei, Xiaodan
Li, Qingzhi
Guo, Junhan
Yang, Geng
Yang, Hong
Cai, Lulu
Liu, Yiyao
Wu, Chunhui
ACTA PHARMACEUTICA SINICA B, 2024, 14 (03) : 1345 - 1361
[49] Biomimetic “Gemini nanoimmunoregulators” orchestrated for boosted photoimmunotherapy by spatiotemporally modulating PD-L1 and tumor-associated macrophages
Honglin Huang
Ningxi Li
Xiaodan Wei
Qingzhi Li
Junhan Guo
Geng Yang
Hong Yang
Lulu Cai
Yiyao Liu
Chunhui Wu
Acta Pharmaceutica Sinica B, 2024, 14 (03) : 1345 - 1361
[50] Prognostic impact of soluble PD-L1 derived from tumor-associated macrophages in non-small-cell lung cancer
Koji Teramoto
Tomoyuki Igarashi
Yoko Kataoka
Mitsuaki Ishida
Jun Hanaoka
Hidetoshi Sumimoto
Yataro Daigo
Cancer Immunology, Immunotherapy, 2023, 72 : 3755 - 3764

← 1 2 3 4 5 →