Optofluidic Platform with Integrated Optical Waveguides and Sample Preparation for Digitized Detection of Nucleic Acid Targets

被引:0
|
作者
Jain, A. [1 ]
Meena, G. G. [1 ]
Stambaugh, A. [1 ]
Patterson, J. L. [2 ]
Hawkins, A. R. [3 ]
Schmidt, H. [1 ]
机构
[1] Univ Calif Santa Cruz, Sch Engn, 1156 High St, Santa Cruz, CA 95064 USA
[2] Texas Biomed Res Inst, Dept Virol & Immunol, 7620 NW Loop 410, San Antonio, TX 78227 USA
[3] Brigham Young Univ, ECEn Dept, 459 Clyde Bldg, Provo, UT 84602 USA
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中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
An architecture of sensitive solid-core and liquid-core optical waveguides are integrated with a pneumatic valve array on a single optofluidic platform to enable specific capture, labeling and detection of single nucleic acid strands using barcode fluorescence reporters. (c) 2019 The Author(s)
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页数:2
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