Down modulation of in vitro reactivity to idiotypic stimulation is correlated with high levels of CD8+ cells, high levels of IL-10 transcription and low expression of IL-2 receptor.

被引:0
|
作者
Dutra, WO
Gollob, KJ
Martins-Filho, OA
Pereira, ME
PintoDias, JC
Brener, ZI
Colley, DG
Gazzinelli, G
CorreaOliveira, R
Coffman, RL
Carvalho, JC
机构
[1] FIOCRUZ MS, CTR PESQUISAS RENE RACHOU, BR-30190002 BELO HORIZONTE, MG, BRAZIL
[2] CDC, DIV PARASIT DIS, ATLANTA, GA USA
[3] DNAX RES INST MOLEC & CELLULAR BIOL INC, PALO ALTO, CA 94304 USA
来源
FASEB JOURNAL | 1996年 / 10卷 / 06期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:194 / 194
页数:1
相关论文
共 50 条
  • [41] Multiple levels of activation of murine CD8+ intraepithelial lymphocytes defined by OX40 (CD134) expression:: Effects on cell-mediated cytotoxicity, IFN-γ, and IL-10 regulation
    Wang, HC
    Klein, JR
    JOURNAL OF IMMUNOLOGY, 2001, 167 (12): : 6717 - 6723
  • [42] IMMUNOREGULATORY FUNCTIONS OF PAF-ACETHER .3. DOWN-REGULATION OF CD4+ T-CELLS HIGH-AFFINITY IL-2 RECEPTOR EXPRESSION
    DULIOUST, A
    DUPREZ, V
    PITTON, C
    SALEM, P
    HEMAR, A
    BENVENISTE, J
    THOMAS, Y
    JOURNAL OF IMMUNOLOGY, 1990, 144 (08): : 3123 - 3129
  • [43] Peripheral blood lymphocytes from low-grade squamous intraepithelial lesions patients recognize vaccine antigens in the presence of activated dendritic cells, and produced high levels of CD8 + IFNγ + T cells and low levels of IL-2 when induced to proliferate
    Jorge Hernández-Montes
    Leticia Rocha-Zavaleta
    Alberto Monroy-García
    Benny Weiss-Steider
    María del Carmen Zaragoza-Ortega
    Fernando Cruz-Talonia
    Omar Cruz y Cruz
    Laura Bonifaz-Alfonso
    Adriana Karina Chávez-Rueda
    Martha Patricia Rojo-Aguilar
    María Victoria Legorreta-Haquet
    María de Lourdes Mora-García
    Infectious Agents and Cancer, 7
  • [44] Loss of CD28 expression on CD8+ T cells is induced by IL-2 receptor γ chain signalling cytokines and type IIFN, and increases susceptibility to activation-induced apoptosis
    Borthwick, NJ
    Lowdell, M
    Salmon, M
    Akbar, AN
    INTERNATIONAL IMMUNOLOGY, 2000, 12 (07) : 1005 - 1013
  • [45] Low and high levels of α-tocopherol exert opposite effects on IL-2 possibly through the modulation of PPAR-γ, IκBα, and apoptotic pathway in activated splenocytes
    Hsieh, CC
    Huang, CJ
    Lin, BF
    NUTRITION, 2006, 22 (04) : 433 - 440
  • [46] Constitutive expression of a chimeric receptor that delivers IL-2/IL-15 signals allows antigen-independent proliferation of CD8+CD44high but not other T cells (vol 164, pg 5659, 2000)
    Gasser, S
    Corthésy, P
    Beerman, F
    MacDonald, HR
    Nabholz, M
    JOURNAL OF IMMUNOLOGY, 2000, 165 (04): : 2313 - 2313
  • [47] Cytokine activation induces CD25 expression and a functional high-affinity IL-2 receptor on CD56dim human NK Cells
    Leong, Jeff
    Chase, Julie
    Romee, Rizwan
    Schneider, Stephanie
    Sullivan, Ryan
    Fehniger, Todd
    JOURNAL OF IMMUNOLOGY, 2013, 190
  • [48] Increased IL-4- and IL-13-producing not only CD4+ T cells but also CD8+ T cells in peripheral blood from atopic dermatitis patients with high levels of serum IgE.
    Sato, A
    Tuji, K
    Kanzaki, H
    Tada, J
    Morita, Y
    Yamamura, M
    Arata, J
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1998, 110 (04) : 665 - 665
  • [49] CD28 co-stimulation results in down-regulation of lymphotactin expression in human CD4+ but not CD8+ T cells via an IL-2-dependent mechanism
    Olive, D
    Cerdan, C
    EUROPEAN JOURNAL OF IMMUNOLOGY, 1999, 29 (08) : 2443 - 2453
  • [50] Peripheral blood lymphocytes from low-grade squamous intraepithelial lesions patients recognize vaccine antigens in the presence of activated dendritic cells, and produced high levels of CD8+IFNγ plus T cells and low levels of IL-2 when induced to proliferate
    Hernandez-Montes, Jorge
    Rocha-Zavaleta, Leticia
    Monroy-Garcia, Alberto
    Weiss-Steider, Benny
    del Carmen Zaragoza-Ortega, Maria
    Cruz-Talonia, Fernando
    Cruz y Cruz, Omar
    Bonifaz-Alfonso, Laura
    Karina Chavez-Rueda, Adriana
    Patricia Rojo-Aguilar, Martha
    Victoria Legorreta-Haquet, Maria
    de Lourdes Mora-Garcia, Maria
    INFECTIOUS AGENTS AND CANCER, 2012, 7