Biosynthesis of streptolydigin: Origin of the oxygen atoms

被引:8
|
作者
Chen, Hao [1 ]
Olesen, Solveig G. [1 ]
Harrison, Paul H. M. [1 ]
机构
[1] McMaster Univ, Dept Chem, Hamilton, ON L8S 4M1, Canada
关键词
D O I
10.1021/ol0621304
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] Biosynthetic incorporations of [C-13, O-18]-labeled precursors into streptolydigin reveal the origin of the oxygen atoms, limiting the possible pathways for acyltetramic acid ring assembly and for formation of the bicyclic ketal.
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页码:5329 / 5332
页数:4
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