Protection against Listeria monocytogenes by ODN containing CpG motifs in BALB/c and C57BL/6 mice

被引：1
|
作者：
Rad, M.
Ahmadi, M.
Hosseini, R. Farid
Ashkar, A. A.
Nejati, M.
Tabaraie, B.
Nourozian, D.
机构：
[1] Urmia Univ, Dept Pathobiol, Fac Vet Med, Orumiyeh, Iran
[2] Mashhad Univ Med Sci, Dept Allergy & Immunol, Mashhad, Iran
[3] McMaster Univ, Dept Pathol & Mol Med, Hlth Sci Ctr, Hamilton, ON, Canada
[4] Pasteur Inst Iran, Dept Bacterial Vaccines, Karaj, Iran
来源：
JOURNAL OF APPLIED ANIMAL RESEARCH | 2006年 / 29卷 / 02期
关键词：
CPG-ODN; Listeria; protection; mice;
D O I：
10.1080/09712119.2006.9706591
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
Synthetic oligodeoxynucleotides containing CpG motifs have been shown to be effective immunoprotective agents in murine models for intracellular bacterial, viral and protozoan infections. In the present study, we demonstrated that CpG-ODN can induce protection against Listeria monocytogenes in BALB/c and C57BL/6 mice, the survival rate being higher in BALB/c mice. Further studies to determine the cause have been recommended.
引用
收藏
页码：145 / 147
页数：3
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