Palladium-Catalyzed Suzuki Cross-Coupling of Arylhydrazines via C-N Bond Cleavage

被引：49

作者：

Peng, Zhimin ^{[1
,2
]}

Hu, Gaobo ^{[1
,2
]}

Qiao, Hongwei ^{[1
,2
]}

Xu, Pengxiang ^{[1
,2
]}

Gao, Yuxing ^{[1
,2
]}

Zhao, Yufen ^{[1
,2
,3
]}

机构：

[1] Xiamen Univ, Dept Chem, Coll Chem & Chem Engn, Xiamen 361005, Fujian, Peoples R China

[2] Xiamen Univ, Key Lab Chem Biol Fujian Prov, Coll Chem & Chem Engn, Xiamen 361005, Fujian, Peoples R China

[3] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing 100084, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 79卷 / 06期

关键词：

DIRECT ARYLATION; CARBON-NITROGEN; LIGAND-FREE; ARYL; WATER; NANOPARTICLES; OLEFINATION; ACTIVATION; REAGENTS; BIARYLS;

D O I：

10.1021/jo500026g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first example of Pd-catalyzed Suzuki cross-coupling of readily available arylhydrazines with arylboronic acids via C-N bond cleavage was developed under air, affording various biaryl compounds with broad substrate applicability and moderate to good yields. Moreover, the rigorous exclusion of air/moisture is not required in these transformations. Thus, the protocol represents a simple and efficient procedure to access biaryl compounds.

引用

页码：2733 / 2738

页数：6

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