THE EFFECT OF NOTCH BLOCKADE WITH DBZ, A GAMMA-SECRETASE INHIBITOR, ON THE IN VITRO AND IN VIVO GROWTH OF A NEUROBLASTOMA CELL LINE

被引：0
|
作者：
Freed, Jennifer [1 ]
Hernandez, Sonia [1 ]
Kandel, Jessica J. [1 ]
Yamashiro, Darrell [1 ]
机构：
[1] Columbia Univ, New York, NY USA
来源：
PEDIATRIC BLOOD & CANCER | 2009年 / 52卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：742 / 742
页数：1
相关论文
共 50 条
  • [41] Gamma-secretase inhibitor DAPT suppresses glioblastoma growth via uncoupling of tumor vessel density from vessel function
    Yuhui Zou
    Yiqun Cao
    Zhijian Yue
    Jianmin Liu
    Clinical and Experimental Medicine, 2013, 13 : 271 - 278
  • [42] Gamma-secretase inhibitor DAPT suppresses glioblastoma growth via uncoupling of tumor vessel density from vessel function
    Zou, Yuhui
    Cao, Yiqun
    Yue, Zhijian
    Liu, Jianmin
    CLINICAL AND EXPERIMENTAL MEDICINE, 2013, 13 (04) : 271 - 278
  • [43] Gamma-secretase inhibitor prevents proliferation and migration of ductus arteriosus smooth muscle cells: a role of Notch signaling in postnatal closure of ductus arteriosus
    Hsu, J. H.
    Wu, J. R.
    Dai, Z. K.
    Yeh, J. L.
    CARDIOVASCULAR RESEARCH, 2016, 111 : S56 - S57
  • [44] Anti-myeloma effect of pharmacological inhibition of Notch/gamma-secretase with RO4929097 is mediated by modulation of tumor microenvironment
    Pisklakova, Alexandra
    Grigson, Eileen
    Ozerova, Maria
    Chen, Feng
    Sullivan, Daniel M.
    Nefedova, Yulia
    CANCER BIOLOGY & THERAPY, 2016, 17 (05) : 477 - 485
  • [45] The allosteric Akt inhibitor MK-2206 inhibits neuroblastoma tumor cell growth in vitro and in vivo
    Li, Zhijie
    Ramalingam, Sridevi
    Yan, Shuang
    Thiele, Carol J.
    CANCER RESEARCH, 2011, 71
  • [46] Gamma-Secretase Inhibitor Treatment Promotes VEGF-A-Driven Blood Vessel Growth and Vascular Leakage but Disrupts Neovascular Perfusion
    Kalen, Mattias
    Heikura, Tommi
    Karvinen, Henna
    Nitzsche, Anja
    Weber, Holger
    Esser, Norbert
    Yla-Herttuala, Seppo
    Hellstrom, Mats
    PLOS ONE, 2011, 6 (04):
  • [47] Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia
    Kaushik, Bhupendra
    Pal, Dilipkumar
    CURRENT DRUG TARGETS, 2021, 22 (15) : 1789 - 1798
  • [48] ErbB-2 inhibition activates notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor: opportunity for a novel therapeutic combination
    Osipo, C.
    Patel, P.
    Hoo, L.
    Whitehouse, L.
    Strack, P.
    Golde, T.
    Albain, K.
    Miele, L.
    BREAST CANCER RESEARCH AND TREATMENT, 2007, 106 : S20 - S20
  • [49] Growth-promoting effect of bisphenol A on neuroblastoma in vitro and in vivo
    Zhu, Haitao
    Xiao, Xianmin
    Zheng, Jicui
    Zheng, Shan
    Dong, Kuiran
    Yu, Yong
    JOURNAL OF PEDIATRIC SURGERY, 2009, 44 (04) : 672 - 680
  • [50] Combined blockade of PI3-kinase and mTOR synergizes with gamma-secretase inhibitors to induce a high level of cell death in T-cell acute lymphoblastic leukaemia cells with activated Notch signalling
    Banerjee, L.
    Mansour, M.
    Khwaja, A.
    BRITISH JOURNAL OF HAEMATOLOGY, 2009, 145 : 9 - 10
12345