Cardiac surgery in low-income settings: 10 years of experience from two countries

被引:28
|
作者
Mirabel, Mariana [1 ,2 ,3 ]
Lachaud, Matthias [4 ,5 ]
Offredo, Lucile. [1 ]
Lachaud, Cecile [4 ]
Zuschmidt, Benjamin [1 ]
Ferreira, Beatriz [4 ]
Sidi, Daniel [2 ,4 ,7 ]
Chauvaud, Sylvain [2 ,6 ]
Sok, Phang [8 ]
Deloche, Alain [2 ,6 ]
Marijon, Eloi [1 ,2 ,3 ]
Jouven, Xavier [1 ,2 ,3 ]
机构
[1] Hop Europeen Georges Pompidou, Paris Cardiovasc Res Ctr, Inserm U970, 56 Rue Leblanc, F-75737 Paris 15, France
[2] Paris Descartes Univ, F-75005 Paris, France
[3] Hop Europeen Georges Pompidou, Dept Cardiol, F-75015 Paris, France
[4] Inst Coracdo ICOR, Maputo 1100, Mozambique
[5] Inst Thorax, F-44093 Nantes 1, France
[6] Chaine Lespoir, F-75014 Paris, France
[7] Necker Enfants Malades Hosp, Dept Paediat Cardiol, F-75015 Paris, France
[8] Ctr Cardiol Phnom Penh, Phnom Penh, Cambodia
关键词
Cardiac surgery; Rheumatic heart disease; Acute rheumatic fever; Congenital heart disease; Developing countries; Global health; RHEUMATIC HEART-DISEASE; VALVE-REPLACEMENT; OUTCOMES; PACIFIC; WESTERN; AFRICA;
D O I
10.1016/j.acvd.2016.05.006
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background - Access to cardiac surgery is limited in low-income settings, and data on patient outcomes are scarce. Aims - To assess characteristics, surgical procedures and outcomes in patients undergoing open-heart surgery in low-income settings. Methods - This was a cohort study (2001-2011) in two low-income countries, Cambodia and Mozambique, where cardiac surgery had been promoted by visiting non-governmental organizations. Results - In Cambodia and Mozambique, respectively, 1332 and 767 consecutive patients were included; 547 (41.16%) and 385 (50.20%) were men; median age at first surgery was 11 years (interquartile range [IQR] 4-14) and 11 years (IQR 3-18); rheumatic heart disease affetted 490 (36.79%) and 268 (34.94%) patients; congenital heart disease (CHD) affected 834 (62.61%) and 390 (50.85%) patients, with increasingly more CHD patients over time (P < 0.001); and the number of patients lost to follow-up reached 741 (55.63%) and 112 (14.6%) at 30 days. A total. of 249 (32.46%) patients were lost to follow-up in Mozambique, remoteness being the only influencing factor (P< 0.001). Among patients with known vital status, the early (<30 days) postoperative mortality rate was 6.10% (n=40) in Mozambique and 3.05% (n= 18) in Cambodia. Overall, 109 (8.18%) patients in Cambodia and 94 (12.26%) patients in Mozambique underwent re-do surgery. In Mozambique, a further 50/518 (9.65%) patients died at a median of 23 months (IQR 7-43); in Cambodia, a further 34/591 (5.75%) patients died at a median of 11.5 months (IQR 6-54.5). Conclusions - Cardiac surgery is feasible in low-income countries with acceptable in-hospital mortality and proof of capacity building. Patient outcomes after cardiac surgery in low-income countries remain unknown, given the strikingly high numbers of lost to follow-up. (C) 2016 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:82 / 90
页数:9
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