Role of P2Y6 Receptor-G α12/13 signaling in pressure overload-induced cardiac fibrosis

被引:0
|
作者
Uemura, Aya [1 ]
Nishida, Motohiro [1 ]
Sato, Yoji [2 ]
Narita, Yusuke [1 ]
Tozaki-Saitoh, Hidetoshi [3 ]
Nakaya, Michio [1 ]
Inoue, Kazuhide [3 ]
Kurose, Hitoshi [1 ]
机构
[1] Kyushu Univ, Dept Pharmacol Toxicol, Grad Sch Pharm Sci, Higashi Ku, Fukuoka 8128582, Japan
[2] NIHS, Div Cell Gene Thpy Prod, Setagaya Ku, Tokyo 1588501, Japan
[3] Kyushu Univ, Grad Sch Pharmaceut Sci, Dept Mol Sys Pharmacol, Higashi Ku, Fukuoka 8128582, Japan
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:117P / 117P
页数:1
相关论文
共 50 条
  • [21] P2Y6 Receptor Signaling Pathway Mediates Inflammatory Responses Induced by Monosodium Urate Crystals
    Uratsuji, Hideya
    Tada, Yayoi
    Kawashima, Tomohiko
    Kamata, Masahiro
    Hau, Carren Sy
    Asano, Yoshihide
    Sugaya, Makoto
    Kadono, Takafumi
    Asahina, Akihiko
    Sato, Shinichi
    Tamaki, Kunihiko
    JOURNAL OF IMMUNOLOGY, 2012, 188 (01): : 436 - 444
  • [22] P2Y6 Receptor Activation Promotes Inflammation and Tissue Remodeling in Pulmonary Fibrosis
    Mueller, Tobias
    Fay, Susanne
    Vieira, Rodolfo Paula
    Karmouty-Quintana, Harry
    Cicko, Sanja
    Ayata, Cemil Korcan
    Zissel, Gernot
    Goldmann, Torsten
    Lungarella, Giuseppe
    Ferrari, Davide
    Di Virgilio, Francesco
    Robaye, Bernard
    Boeynaems, Jean-Marie
    Lazarowski, Eduardo R.
    Blackburn, Michael R.
    Idzko, Marco
    FRONTIERS IN IMMUNOLOGY, 2017, 8
  • [23] Cavin-2/SDPR in Cardiac Fibroblasts Modulates TGF-[beta]/Smad Signaling and Promotes Pressure Overload-induced Fibrosis
    Higuchi, Yusuke
    Ogata, Takehiro
    Nakanishi, Naohiko
    Nishi, Masahiro
    Sakamoto, Akira
    Tsuji, Yumika
    Matoba, Satoaki
    CIRCULATION RESEARCH, 2019, 125
  • [24] Knockout of β1- and β2-adrenoceptors attenuates pressure overload-induced cardiac hypertrophy and fibrosis
    Kiriazis, H.
    Wang, K.
    Xu, Q.
    Gao, X-M
    Ming, Z.
    Su, Y.
    Moore, X-L
    Lambert, G.
    Gibbs, M. E.
    Dart, A. M.
    Du, X-J
    BRITISH JOURNAL OF PHARMACOLOGY, 2008, 153 (04) : 684 - 692
  • [25] Central Role of P2Y6 UDP Receptor in Arteriolar Myogenic Tone
    Kauffenstein, Gilles
    Tamareille, Sophie
    Prunier, Fabrice
    Roy, Charlotte
    Ayer, Audrey
    Toutain, Bertrand
    Billaud, Marie
    Isakson, Brant E.
    Grimaud, Linda
    Loufrani, Laurent
    Rousseau, Pascal
    Abraham, Pierre
    Procaccio, Vincent
    Monyer, Hannah
    de Wit, Cor
    Boeynaems, Jean-Marie
    Robaye, Bernard
    Kwak, Brenda R.
    Henrion, Daniel
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2016, 36 (08) : 1598 - 1606
  • [26] P2Y6 Receptor-Mediated Proinflammatory Signaling in Human Bronchial Epithelia
    Hao, Yuan
    Liang, Jocelyn F.
    Chow, Alison W.
    Cheung, Wing-tai
    Ko, Wing-hung
    PLOS ONE, 2014, 9 (09):
  • [27] Omega-3 Fatty Acids Prevent Pressure Overload-Induced Cardiac Fibrosis Through Activation of Cyclic GMP/Protein Kinase G Signaling in Cardiac Fibroblasts
    Chen, Jinghai
    Shearer, Gregory C.
    Chen, Quanhai
    Healy, Chastity L.
    Beyer, April J.
    Nareddy, Vijaya B.
    Gerdes, A. Martin
    Harris, William S.
    O'Connell, Timothy D.
    Wang, Dajun
    CIRCULATION, 2011, 123 (06) : 584 - +
  • [28] Edaravone inhibits pressure overload-induced cardiac fibrosis and dysfunction by reducing expression of angiotensin II AT1 receptor
    Zhang, Wei-Wei
    Bai, Feng
    Wang, Jin
    Zheng, Rong-Hua
    Yang, Li-Wang
    James, Erskine A.
    Zhao, Zhi-Qing
    DRUG DESIGN DEVELOPMENT AND THERAPY, 2017, 11 : 3019 - 3033
  • [29] Partial inhibition of activin receptor-like kinase 4 attenuates pressure overload-induced cardiac fibrosis and improves cardiac function
    Li, Chang-Yi
    Chen, Yi-He
    Wang, Qian
    Hou, Jian-Wen
    Wang, Hong
    Wang, Yue-Peng
    Li, Yi-Gang
    JOURNAL OF HYPERTENSION, 2016, 34 (09) : 1766 - 1777
  • [30] MicroRNA-323a-3p Promotes Pressure Overload-Induced Cardiac Fibrosis by Targeting TIMP3
    Zhang, JingChao
    Lang, Yan
    Guo, LongHui
    Pei, Yu
    Hao, Shuang
    Liang, ZhenXing
    Su, Gang
    Shu, LiLiang
    Liu, Hai
    Huang, Chen
    Xu, Jing
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 50 (06) : 2176 - 2187