Ghrelin Gene Products in Acute and Chronic Inflammation

被引：36
|
作者：
Prodam, Flavia [1 ]
Filigheddu, Nicoletta [2 ]
机构：
[1] Univ Piemonte Orientale Amedeo Avogadro, Dept Hlth Sci, Novara, Italy
[2] Univ Piemonte Orientale Amedeo Avogadro, Dept Translat Med, Via Solaroli 17, I-28100 Novara, Italy
来源：
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS | 2014年 / 62卷 / 05期
关键词：
Acylated ghrelin; Unacylated ghrelin; Obestatin; Autoimmune disease; Inflammatory disease; DES-ACYL GHRELIN; HORMONE-RELEASING PEPTIDE; KAPPA-B ACTIVATION; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; VITREOUS CYTOKINE LEVELS; PANCREATIC BETA-CELLS; EMBRYONIC STEM-CELLS; BODY-MASS INDEX; PLASMA GHRELIN; UNACYLATED GHRELIN;
D O I：
10.1007/s00005-014-0287-9
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Ghrelin gene products-the peptides ghrelin, unacylated ghrelin, and obestatin-have several actions on the immune system, opening new perspectives within neuroendocrinology, metabolism and inflammation. The aim of this review is to summarize the available evidence regarding the less known role of these peptides in the machinery of inflammation and autoimmunity, outlining some of their most promising therapeutic applications.
引用
收藏
页码：369 / 384
页数：16
相关论文
共 50 条
  • [21] Ghrelin gene products, receptors, and GOAT enzyme: biological and pathophysiological insight
    Gahete, Manuel D.
    Rincon-Fernandez, David
    Villa-Osaba, Alicia
    Hormaechea-Agulla, Daniel
    Ibanez-Costa, Alejandro
    Martinez-Fuentes, Antonio J.
    Gracia-Navarro, Francisco
    Castano, Justo P.
    Luque, Raul M.
    JOURNAL OF ENDOCRINOLOGY, 2014, 220 (01) : R1 - R24
  • [22] At the Cutting Edge: Ghrelin Gene Products in Food Intake and Gut Motility
    Chen, Chih-Yen
    Fujimiya, Mineko
    Asakawa, Akihiro
    Chang, Full-Young
    Cheng, Juei-Tang
    Lee, Shou-Dong
    Inui, Akio
    NEUROENDOCRINOLOGY, 2009, 89 (01) : 9 - 17
  • [23] Galectins: regulators of acute and chronic inflammation
    Liu, Fu-Tong
    Rabinovich, Gabriel A.
    YEAR IN IMMUNOLOGY 2, 2010, 1183 : 158 - 182
  • [24] DIFFERENCES BETWEEN ACUTE AND CHRONIC INFLAMMATION
    Wong, S.
    Devlin, J. P.
    INFLAMMATION RESEARCH, 2010, 59 : S297 - S297
  • [25] ACUTE AND CHRONIC INFLAMMATION - CHAIRMANS SUMMARY
    WAKSMAN, BH
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1974, 221 (FEB28) : 376 - 382
  • [26] Inflammation and acute exacerbations of chronic bronchitis
    Sethi, S
    Murphy, TF
    CHEST, 2001, 120 (04) : 1423 - 1423
  • [27] Monocyte trafficking in acute and chronic inflammation
    Ingersoll, Molly A.
    Platt, Andrew M.
    Potteaux, Stephane
    Randolph, Gwendalyn J.
    TRENDS IN IMMUNOLOGY, 2011, 32 (10) : 470 - 477
  • [28] The contribution of inflammation to acute and chronic neurodegeneration
    Perry, VH
    Bolton, SJ
    Anthony, DC
    Betmouni, S
    RESEARCH IN IMMUNOLOGY, 1998, 149 (7-8): : 721 - 725
  • [29] Redox regulation in acute and chronic inflammation
    M Maccarrone
    B Brüne
    Cell Death & Differentiation, 2009, 16 : 1184 - 1186
  • [30] Pathological Acute Inflammation in Chronic Pancreatitis
    Vijayaraj, Pavankumar
    Pottakkat, Biju
    Kalayarasan, Raja
    Chandrasekar, Sandip
    Verma, Surinder Kumar
    JOURNAL OF THE PANCREAS, 2019, 20 (06): : 167 - 170
12345