Ghrelin Gene Products in Acute and Chronic Inflammation

被引：36
|
作者：
Prodam, Flavia [1 ]
Filigheddu, Nicoletta [2 ]
机构：
[1] Univ Piemonte Orientale Amedeo Avogadro, Dept Hlth Sci, Novara, Italy
[2] Univ Piemonte Orientale Amedeo Avogadro, Dept Translat Med, Via Solaroli 17, I-28100 Novara, Italy
来源：
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS | 2014年 / 62卷 / 05期
关键词：
Acylated ghrelin; Unacylated ghrelin; Obestatin; Autoimmune disease; Inflammatory disease; DES-ACYL GHRELIN; HORMONE-RELEASING PEPTIDE; KAPPA-B ACTIVATION; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; VITREOUS CYTOKINE LEVELS; PANCREATIC BETA-CELLS; EMBRYONIC STEM-CELLS; BODY-MASS INDEX; PLASMA GHRELIN; UNACYLATED GHRELIN;
D O I：
10.1007/s00005-014-0287-9
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Ghrelin gene products-the peptides ghrelin, unacylated ghrelin, and obestatin-have several actions on the immune system, opening new perspectives within neuroendocrinology, metabolism and inflammation. The aim of this review is to summarize the available evidence regarding the less known role of these peptides in the machinery of inflammation and autoimmunity, outlining some of their most promising therapeutic applications.
引用
收藏
页码：369 / 384
页数：16
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