DNA vaccines against anthrax

被引：14

作者：

Galloway, DR ^{[1
]}

Baillie, L ^{[1
]}

机构：

[1] USN, Med Res Ctr, Biodef Res Directorate, Silver Spring, MD 20903 USA

来源：

EXPERT OPINION ON BIOLOGICAL THERAPY | 2004年 / 4卷 / 10期

关键词：

anthrax; Bacillus anthracis; DNA vaccine; genetic immunisation; lethal factor; protective antigen;

D O I：

10.1517/14712598.4.10.1661

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

DNA vaccination is vaccination at its simplest. Due to renewed interest in vaccination against anthrax and other biothreat agents, a genetic immunisation approach offers attractive possibilities for rapid, responsive vaccine development. DNA vaccination against anthrax is an active area of research showing promising results at present, which in the short-term and in the future could form the basis for new advances in multi-agent vaccine development. The anthrax 'model' constitutes an important experimental system for genetic immunisation technology development.

引用

页码：1661 / 1667

页数：7

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