Sequence-specific 1H, 15N and 13C resonance assignments of Art v 1: a proline-rich allergen of Artemisia vulgaris pollen

被引:5
|
作者
Razzera, Guilherme [1 ]
Gadermaier, Gabriele [2 ]
Almeida, Marcius S. [1 ]
Ferreira, Fatima [2 ]
Almeida, Fabio C. L. [1 ]
Valente, Ana Paula [1 ]
机构
[1] Univ Fed Rio de Janeiro, Ctr Nacl Ressonancia Magnet Nucl, Inst Bioquim Med, Rio De Janeiro, Brazil
[2] Salzburg Univ, Christian Doppler Lab Allergy Diag & Therapy, A-5020 Salzburg, Austria
关键词
Art v 1; NMR assignments; Proline-rich allergen; Defensin-like; MUGWORT POLLEN;
D O I
10.1007/s12104-009-9151-y
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Art v 1 is the major allergen of Artemisia vulgaris. The IgE raised against Art v 1 not only can cross-react with other proteins from the Asteraceae family members but also with components of various forms of food. Art v 1 is an important target for immunotherapy strategies, including vaccination with hypoallergenic derivatives or chimeras. We report the H-1, C-13, and N-15 resonance assignments of the recombinant Art v 1 and identification of secondary structures based on C-13 chemical shifts.
引用
收藏
页码:103 / 106
页数:4
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