Characterization of human cytochrome p450 enzymes responsible for the metabolism of lonafarnib (Sarasar™)

被引:0
|
作者
Ghosal, Anima [1 ]
Chowdhury, Swapan K. [1 ]
Tong, Wei [1 ]
Hapangama, Neil [1 ]
Yuan, Yuan [1 ]
Su, Ai-Duen [1 ]
Zbaida, Shmuel [1 ]
机构
[1] Schering Plough Res Inst, Dept DMPK, Kenilworth, NJ USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
390
引用
收藏
页码:254 / 254
页数:1
相关论文
共 50 条
  • [31] Metabolism of 3-methylindole by porcine liver microsomes: Responsible cytochrome P450 enzymes
    Diaz, GJ
    Squires, EJ
    TOXICOLOGICAL SCIENCES, 2000, 55 (02) : 284 - 292
  • [32] Metabolism of carcinogenic alpha-asarone by human cytochrome P450 enzymes
    Alexander T. Cartus
    Dieter Schrenk
    Naunyn-Schmiedeberg's Archives of Pharmacology, 2020, 393 : 213 - 223
  • [33] Metabolism of carcinogenic alpha-asarone by human cytochrome P450 enzymes
    Cartus, Alexander T.
    Schrenk, Dieter
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2020, 393 (02) : 213 - 223
  • [34] In vitro metabolism of naphthalene by human liver microsomal cytochrome P450 enzymes
    Cho, TM
    Rose, RL
    Hodgson, E
    DRUG METABOLISM AND DISPOSITION, 2006, 34 (01) : 176 - 183
  • [35] Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin
    Svensson, USH
    Ashton, M
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1999, 48 (04) : 528 - 535
  • [36] Metabolism of clozapine by cDNA-expressed human cytochrome P450 enzymes
    Linnet, K
    Olesen, OV
    DRUG METABOLISM AND DISPOSITION, 1997, 25 (12) : 1379 - 1382
  • [37] Role of individual human cytochrome P450 enzymes in the in vitro metabolism of hydromorphone
    Benetton, SA
    Borges, VM
    Chang, TKH
    Mcerlane, KM
    XENOBIOTICA, 2004, 34 (04) : 335 - 344
  • [38] Cytochrome p450 enzymes
    Donaldson, D
    JOURNAL OF THE ROYAL SOCIETY FOR THE PROMOTION OF HEALTH, 2000, 120 (03): : 150 - 151
  • [39] Characterization of the metabolism of fenretinide by human liver microsomes, cytochrome P450 enzymes and UDP-glucuronosyltransferases
    Illingworth, N. A.
    Boddy, A. V.
    Daly, A. K.
    Veal, G. J.
    BRITISH JOURNAL OF PHARMACOLOGY, 2011, 162 (04) : 989 - 999
  • [40] In vitro characterization of the metabolism of haloperidol using recombinant cytochrome P450 enzymes and human liver microsomes
    Fang, J
    McKay, G
    Song, JX
    Remillrd, A
    Li, XM
    Midha, K
    DRUG METABOLISM AND DISPOSITION, 2001, 29 (12) : 1638 - 1643