Varying the Constant: Mechanisms of Fc-Mediated Immunity to Influenza Virus

被引：0

作者：

Kastenschmidt, Jenna M. ^{[1
,2
]}

Wagar, Lisa E. ^{[1
,2
]}

机构：

[1] Univ Calif Irvine, Dept Physiol & Biophys, Irvine, CA 92717 USA

[2] Univ Calif Irvine, Inst Immunol, Irvine, CA 92717 USA

来源：

CELL HOST & MICROBE | 2020年 / 28卷 / 06期

关键词：

ANTIBODIES;

D O I：

10.1016/j.chom.2020.11.009

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Antibodies are typically thought to mediate antiviral immunity by blocking host-cell infection. However, immunoglobulin G (IgG) can also stimulate antiviral responses through its constant region. A recent study in Nature (Bournazos et al., 2020) shows that modifying Fc binding affinities to better target Fc.RIIa enhances the influenza CD8 T cell response.

引用

页码：769 / 770

页数：2

共 50 条

[41] In-depth analysis of Respiratory Syncytial Virus-specific Fc-mediated antibody effector functions in children and adults
Lakerveld, Anke
Schepp, Rutger
Gelderloos, Anne
Rots, Nynke
van Kasteren, Puck
EUROPEAN JOURNAL OF IMMUNOLOGY, 2024, 54 : 1716 - 1716
[42] PERSISTENCE OF CELL-MEDIATED-IMMUNITY TO INFLUENZA-A VIRUS IN MICE
ASHMAN, RB
IMMUNOLOGY, 1982, 47 (01) : 165 - 168
[43] Neutrophil transepithelial migration: regulation at the apical epithelial surface by Fc-mediated events
Reaves, TA
Colgan, SP
Selvaraj, P
Pochet, MM
Walsh, S
Nusrat, A
Liang, TW
Madara, JL
Parkos, CA
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2001, 280 (04): : G746 - G754
[44] HIV-1 Vpu restricts Fc-mediated effector functions in vivo
Prevost, Jeremie
Anand, Sai Priya
Rajashekar, Jyothi Krishnaswamy
Zhu, Li
Richard, Jonathan
Goyette, Guillaume
Medjahed, Halima
Gendron-Lepage, Gabrielle
Chen, Hung-Ching
Chen, Yaozong
Horwitz, Joshua A.
Grunst, Michael W.
Zolla-Pazner, Susan
Haynes, Barton F.
Burton, Dennis R.
Flavell, Richard A.
Kirchhoff, Frank
Hahn, Beatrice H.
Smith, Amos B.
Pazgier, Marzena
Nussenzweig, Michel C.
Kumar, Priti
Finzi, Andres
CELL REPORTS, 2022, 41 (06):
[45] Pathogen reduction technologies need to evaluate Fc-mediated antibody functions Response
Bagri, Anil
Irsch, Johannes
Corash, Laurence
TRANSFUSION, 2022, 62 (08) : 1681 - 1682
[46] Morphine inhibits Fc-mediated phagocytosis through mu and delta opioid receptors
Tomassini, N
Renaud, F
Roy, S
Loh, HH
JOURNAL OF NEUROIMMUNOLOGY, 2004, 147 (1-2) : 131 - 133
[47] Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination
Adams, Lily E.
Leist, Sarah R.
Dinnon III, Kenneth H.
West, Ande
Gully, Kendra L.
Anderson, Elizabeth J.
Loome, Jennifer F.
Madden, Emily A.
Powers, John M.
Schafer, Alexandra
Sarkar, Sanjay
Castillo, Izabella N.
Maron, Jenny S.
McNamara, Ryan P.
Bertera, Harry L.
Zweigert, Mark R.
Higgins, Jaclyn S.
Hampton, Brea K.
Premkumar, Lakshmanane
Alter, Galit
Montgomery, Stephanie A.
Baxter, Victoria K.
Heise, Mark T.
Baric, Ralph S.
CELL REPORTS, 2023, 42 (04):
[48] FC-MEDIATED IMMUNE PRECIPITATION .3. VISUALIZATION BY ELECTRON-MICROSCOPY
MOLLER, NPH
CHRISTIANSEN, G
IMMUNOLOGY, 1983, 48 (03) : 469 - 476
[49] Understudied Factors Influencing Fc-Mediated Immune Responses against Viral Infections
Anand, Sai Priya
Finzi, Andres
VACCINES, 2019, 7 (03)
[50] HETEROSUBTYPIC IMMUNITY TO INFLUENZA TYPE-A VIRUS IN MICE - EFFECTOR MECHANISMS AND THEIR LONGEVITY
LIANG, SH
MOZDZANOWSKA, K
PALLADINO, G
GERHARD, W
JOURNAL OF IMMUNOLOGY, 1994, 152 (04): : 1653 - 1661

← 1 2 3 4 5 →