Development of a Quantitative Systems Pharmacology (QSP) Platform to Support Translational Research and Clinical Development in Immuno-Oncology

被引:0
|
作者
Schmidt, Brian J. [1 ]
Bartlett, Derek W. [2 ]
Agrawal, Shruti [1 ]
Reed, Michael [2 ]
Jure-Kunkel, Maria [1 ]
Gutierrez, Andres A. [1 ]
Clynes, Raphael A. [1 ]
Fischer, Bruce S. [1 ]
Surywanshi, Satyendra [1 ]
Kadambi, Ananth [2 ]
Friedrich, Christina [2 ]
Kudrycki, Katherine [2 ]
Roy, Amit [1 ]
Leil, Tarek A. [1 ]
机构
[1] Bristol Myers Squibb Co, Princeton, NJ USA
[2] Rosa & Co, San Carlos, CA USA
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
M-27
引用
收藏
页码:S22 / S23
页数:2
相关论文
共 50 条
  • [31] Development and validation of a phenotypic screening platform for the identification of novel immuno-oncology targets
    Rabolli, Virginie
    Martini, Murielle
    Scoumanne, Ariane
    Letellier, Marie-Claire
    Crosignani, Stefano
    Queva, Christophe
    Detheux, Michel
    Swiercz, Jakub M.
    Cauwenberghs, Sandra
    CANCER IMMUNOLOGY RESEARCH, 2016, 4 (11)
  • [32] The Challenge for Development of Valuable Immuno-oncology Biomarkers
    Mehnert, Janice M.
    Monjazeb, Arta M.
    Beerthuijzen, Johanna M. T.
    Collyar, Deborah
    Rubinstein, Larry
    Harris, Lyndsay N.
    CLINICAL CANCER RESEARCH, 2017, 23 (17) : 4970 - 4979
  • [33] Immuno-oncology drug development goes global
    Yu, Jia Xin
    Hubbard-Lucey, Vanessa M.
    Tang, Jun
    NATURE REVIEWS DRUG DISCOVERY, 2019, 18 (12) : 899 - 900
  • [34] Lights and Shadows in Immuno-Oncology Drug Development
    Bergamino Sirven, Milana
    Pernas, Sonia
    Cheang, Maggie C. U.
    CANCERS, 2021, 13 (04) : 1 - 11
  • [35] Development of a Quantitative Systems Pharmacology (QSP) Model, the Respiratory PhysioPD™ Platform, to Investigate Biological Mechanisms Underlying Bronchoconstriction
    Friedrich, Christina
    Weber, Ben
    Pryor, Meghan
    Witt, Colleen
    Borghardt, Jens
    Disse, Bernd
    Dallinger, Claudia
    Gupta, Abhya
    Singh, Dave
    Jung, Birgit
    Fowler, Andy
    JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, 2018, 45 : S16 - S17
  • [36] Preclinical tumor models in humanized mice for translational immuno-oncology research
    Stecklum, Maria
    Wulf-Goldenberg, Annika
    Paterka, Magdalena
    Brzezicha, Bernadette
    Fichtner, Iduna
    Hoffmann, Jens
    MOLECULAR CANCER THERAPEUTICS, 2018, 17 (01)
  • [37] Development of a natural killer (NK) ImmunoGraft platform for the evaluation of the pharmacodynamics of immuno-oncology therapeutics
    Verma, Bhavana
    Ruggeri, Bruce
    Weidanz, Jon
    Wesa, Amy
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [38] Development of advanced human immune system mouse models for pre-clinical research in immuno-oncology
    Mossu, A.
    Tschumi, B.
    ANNALS OF ONCOLOGY, 2019, 30
  • [39] Recent advances in the development of AHR antagonists in immuno-oncology
    Sun, Lijun
    RSC MEDICINAL CHEMISTRY, 2021, 12 (06): : 902 - 914
  • [40] Immuno-Oncology: The Third Paradigm in Early Drug Development
    Martin-Liberal, Juan
    Hierro, Cinta
    Ochoa de Olza, Maria
    Rodon, Jordi
    TARGETED ONCOLOGY, 2017, 12 (02) : 125 - 138