Rho-kinase inhibitor enhances corneal endothelial cell proliferation via p27 degradation

被引:0
|
作者
Numata, Ryohei [1 ,2 ]
Okumura, Naoki [1 ,2 ]
Kay, EunDuck [1 ]
Nakahara, Makiko [1 ]
Nakano, Shinichiro [1 ]
Ueno, Morio [2 ]
Kinoshita, Shigeru [2 ]
Koizumi, Noriko [1 ]
机构
[1] Doshisha Univ, Biomed Engn, Kyotanabe, Japan
[2] Kyoto Prefectural Univ Med, Ophthalmol, Kyoto, Japan
关键词
481 cornea: endothelium; 480 cornea: basic science; 654; proliferation;
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
1690
引用
收藏
页数:3
相关论文
共 50 条
  • [41] Simvastatin Attenuated Cerebrovascular Cell Proliferation in the Development of Hypertension Through Rho/Rho-kinase Pathway
    Ma, Ming-Ming
    Li, Shi-Yang
    Wang, Mi
    Guan, Yong-Yuan
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2012, 59 (06) : 576 - 582
  • [42] The effect of endothelin-1 on P27 expression, proliferation and wound healing of bovine corneal endothelial cells
    Crawford, KM
    Achanta, VLS
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 : U522 - U522
  • [43] Cyclin-Dependent Kinase Inhibitor 3 Promotes Cancer Cell Proliferation and Tumorigenesis in Nasopharyngeal Carcinoma by Targeting p27
    Wang, Huimin
    Chen, Hexin
    Zhou, Hang
    Yu, Wenfa
    Lu, Zhenmin
    ONCOLOGY RESEARCH, 2017, 25 (09) : 1431 - 1440
  • [44] Mesangial cell proliferation mediated by PDGF and bFGF is determined by levels of the cyclin kinase inhibitor p27(Kip1)
    Shankland, SJ
    Pippin, J
    Flanagan, M
    Coats, SR
    Nangaku, M
    Gordon, KL
    Roberts, JM
    Couser, WG
    Johnson, RJ
    KIDNEY INTERNATIONAL, 1997, 51 (04) : 1088 - 1099
  • [45] Corneal Endothelial Cell Migration and Proliferation Enhanced by Rho Kinase (ROCK) Inhibitors in In Vitro and In Vivo Models
    Meekins, Landon C.
    Rosado-Adames, Noel
    Maddala, Rupalatha
    Zhao, Jiagang J.
    Rao, Ponugoti V.
    Afshari, Natalie A.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (15) : 6731 - 6738
  • [46] Effect of the Rho-kinase Inhibitor Netarsudil on Corneal Neovascularization in an Alkali-Burn Mouse Model
    Gulati, Reeti Kiran
    Janetos, Timothy
    Basti, Surendra
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2022, 63 (07)
  • [47] Cell-injection Therapy Using Rho Kinase Inhibitor in a Corneal Endothelial Dysfunction Rabbit Model
    Kitano, Junji
    Okumura, Naoki
    Kay, EunDuck
    Ueno, Morio
    Hamuro, Junji
    Kinoshita, Shigeru
    Koizumi, Noriko
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2013, 54 (15)
  • [48] Rho kinase inhibitor promotes cell adhesion of corneal endothelial cells through inhibiting phosphorylation of MLC
    Tsujimoto, Yuki
    Okumura, Naoki
    Kay, EunDuck
    Numata, Ryohei
    Kinoshita, Shigeru
    Koizumi, Noriko
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2013, 54 (15)
  • [49] Thrombin suppresses human endothelial nitric oxide synthase expression via Rho/Rho-kinase pathway
    Rathgeb, L
    Eto, M
    Barabdier, C
    Lüscher, TF
    Yang, Z
    EUROPEAN HEART JOURNAL, 2000, 21 : 65 - 65
  • [50] The role of cyclin-dependent kinase inhibitor p27 in squamous cell carcinoma of the esophagus
    Shibata, H
    Matsubara, O
    Wakiyama, H
    Tanaka, S
    PATHOLOGY RESEARCH AND PRACTICE, 2001, 197 (03) : 157 - 164