SIGNALING PATHWAYS OF IL-6-MEDIATED DOWN-REGULATION OF DRUG DETOXIFICATION CAPACITY IN HUMAN HEPATOCYTES

被引：0
|
作者：
Klein, Marcus [1 ]
Kandel, Benjamin A. [1 ]
Thomas, Maria [1 ]
Hofmann, Ute [1 ]
Metzger, Ute [2 ]
Templin, Markus [2 ]
Damm, Georg [3 ]
Zanger, Ulrich M. [1 ]
机构：
[1] Dr Margarete Fischer Bosch Inst Clin Pharmacol, Stuttgart, Germany
[2] Univ Tubingen, Nat & Med Sci Inst NMI, Reutlingen, Germany
[3] Charite, Dept Gen Visceral & Transplantat Surg, D-13353 Berlin, Germany
来源：
DRUG METABOLISM REVIEWS | 2014年 / 45卷
关键词：
INTERLEUKIN-6;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：87 / 87
页数：1
相关论文
共 50 条
  • [21] Pregnane X receptor is required for interleukin-6-mediated down-regulation of cytochrome P450 3A4 in human hepatocytes
    Yang, Jian
    Hao, Chunshu
    Yang, Dongfang
    Shi, Deshi
    Song, Xiulong
    Luan, Xiaofei
    Hu, Gang
    Yan, Bingfang
    TOXICOLOGY LETTERS, 2010, 197 (03) : 219 - 226
  • [22] Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A
    Akira Ikari
    Chiaki Okude
    Hayato Sawada
    Tadanobu Takahashi
    Junko Sugatani
    Masao Miwa
    Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, 377 : 333 - 343
  • [23] Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A
    Ikari, Akira
    Okude, Chiaki
    Sawada, Hayato
    Takahashi, Tadanobu
    Sugatani, Junko
    Miwa, Masao
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2008, 377 (4-6) : 333 - 343
  • [24] Down-regulation of CC chemokine receptor 3 protein and mRNA in human eosinophils mediated by IL-3
    Dulkys, Y
    Kluthe, C
    Buschermöhle, T
    Barg, I
    Knöl, S
    Kapp, A
    Proudfoot, A
    Elsner, J
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2002, 109 (01) : S64 - S64
  • [25] Envelope protein-mediated down-regulation of hepatitis B virus receptor in infected hepatocytes
    Breiner, KM
    Urban, S
    Glass, B
    Schaller, H
    JOURNAL OF VIROLOGY, 2001, 75 (01) : 143 - 150
  • [26] Differential TGF-beta signaling in glial subsets underlies IL-6-mediated epileptogenesis in mice
    Vinogradov, Ekaterina
    Levy, Nitzan Tagel
    Milikovsky, Dan
    Baranuskas, Gytis
    David, Yaron
    Ketzef, Maya
    Abutbul, Shai
    Weissberg, Itai
    Fleidervish, Ilya
    Friedman, Alon
    Monsonego, Alon
    JOURNAL OF NEUROIMMUNOLOGY, 2014, 275 (1-2) : 108 - 109
  • [27] Small interfering RNA-mediated down-regulation of caveolin-1 differentially modulates signaling pathways in endothelial cells
    Gonzalez, E
    Nagiel, A
    Lin, AJ
    Golan, DE
    Michel, T
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (39) : 40659 - 40669
  • [28] Down-regulation of the β-chemokine receptor CCR6 in dendritic cells mediated by TNF-α and IL-4
    Carramolino, L
    Kremer, L
    Goya, I
    Varona, R
    Buesa, JM
    Gutiérrez, J
    Zaballos, A
    Martínez-A, C
    Márquez, G
    JOURNAL OF LEUKOCYTE BIOLOGY, 1999, 66 (05) : 837 - 844
  • [29] Up-regulation of production of TGF-β and IL-4 and down-regulation of IL-6 by apoptotic human bronchial epithelial cells
    Hodge, S
    Hodge, G
    Flower, R
    Reynolds, PN
    Scicchiatano, R
    Holmes, M
    IMMUNOLOGY AND CELL BIOLOGY, 2002, 80 (06): : 537 - 543
  • [30] Down-regulation of survival signaling through MAPK and Akt in occludin-deficient mouse hepatocytes in vitro
    Murata, M
    Kojima, T
    Yamamoto, T
    Go, M
    Takano, K
    Osanai, M
    Chiba, H
    Sawada, N
    EXPERIMENTAL CELL RESEARCH, 2005, 310 (01) : 140 - 151
12345