Tracers progress for positron emission tomography imaging of glial-related disease

被引：3
|
作者：
Haoran, Jia [1 ]
Tianwu, Xie [1 ,2 ]
机构：
[1] Fudan Univ, Inst Radiat Med, Shanghai 200032, Shanghai, Peoples R China
[2] Fudan Univ, Inst Radiat Med cine, 2094 Xietu Rd, Shanghai 200032, Peoples R China
来源：
JOURNAL OF BIOMEDICAL RESEARCH | 2022年 / 36卷 / 05期
关键词：
glia; positron emission tomography tracer; glioma; Alzheimer's disease; neuroinflammation; MILD COGNITIVE IMPAIRMENT; CENTRAL-NERVOUS-SYSTEM; 18-KDA TRANSLOCATOR PROTEIN; TSPO PET LIGAND; IN-VIVO; BENZODIAZEPINE-RECEPTOR; ALZHEIMERS-DISEASE; TAU-PATHOLOGY; C-11-METHIONINE PET; BRAIN-TUMORS;
D O I：
10.7555/JBR.36.20220017
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Glial cells play an essential part in the neuron system. They can not only serve as structural blocks in the human brain but also participate in many biological processes. Extensive studies have shown that astrocytes and microglia play an important role in neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, as well as glioma, epilepsy, ischemic stroke, and infections. Positron emission tomography is a functional imaging technique providing molecular-level information before anatomic changes are visible and has been widely used in many above-mentioned diseases. In this review, we focus on the positron emission tomography tracers used in pathologies related to glial cells, such as glioma, Alzheimer's disease, and neuroinflammation.
引用
收藏
页码：321 / 335
页数：16
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