MECHANISM-BASED INHIBITION OF HUMAN CARBOXYLESTERASE 2 BY IRINOTECAN

被引：0
|
作者：
Mikamoto, Masaki [1 ]
Fukuda, Katsuyuki [1 ]
Kusano, Kazutomi [2 ]
机构：
[1] Eisai & Co Ltd, Dept Drug Metab & Pharmacokinet Japan, Tsukuba, Ibaraki, Japan
[2] Eisai & Co Ltd, Dept Global Drug Metab & Pharmacokinet, Tsukuba, Ibaraki, Japan
来源：
DRUG METABOLISM REVIEWS | 2015年 / 47卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P362
引用
收藏
页码：209 / 210
页数：2
相关论文
共 50 条
  • [31] MECHANISM-BASED INHIBITION OF DOPAMINE-BETA-HYDROXYLASE
    FLORY, DR
    FITZPATRICK, PF
    HUNTER, TJ
    VILLAFRANCA, JJ
    FEDERATION PROCEEDINGS, 1986, 45 (06) : 1538 - 1538
  • [32] Mechanism-based inhibition and stereochemistry of glucosinolate hydrolysis by myrosinase
    Cottaz, S
    Henrissat, B
    Driguez, H
    BIOCHEMISTRY, 1996, 35 (48) : 15256 - 15259
  • [33] Human carboxylesterase 2 is commonly expressed in tumor tissue and is correlated with activation of irinotecan.
    Xu, G
    Zhang, W
    Ma, MK
    McLeod, H
    CLINICAL CANCER RESEARCH, 2001, 7 (11) : 3736S - 3736S
  • [34] Pharmacogenetics of human carboxylesterase 2, an enzyme involved in the activation of irinotecan into SN-38
    Charasson, V
    Bellott, R
    Meynard, D
    Longy, M
    Gorry, P
    Robert, J
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2004, 76 (06) : 528 - 535
  • [35] Apparent mechanism-based inhibition of human CYP2D6 in vitro by paroxetine: Comparison with fluoxetine and quinidine
    Bertelsen, KM
    Venkatakrishnan, K
    Von Moltke, LL
    Obach, RS
    Greenblatt, DJ
    DRUG METABOLISM AND DISPOSITION, 2003, 31 (03) : 289 - 293
  • [36] Mechanism-based inhibition of human cytochrome p450 1A1 by rhapontigenin
    Chun, YJ
    Ryu, SY
    Jeong, TC
    Kim, MY
    DRUG METABOLISM AND DISPOSITION, 2001, 29 (04) : 389 - 393
  • [37] ISOFORM-SELECTIVE MECHANISM-BASED INHIBITION OF HUMAN CYTOCHROME-P450 1A2 BY FURAFYLLINE
    KUNZE, KL
    TRAGER, WF
    CHEMICAL RESEARCH IN TOXICOLOGY, 1993, 6 (05) : 649 - 656
  • [38] Mechanism-based and computational modeling of hydrogen sulfide biogenesis inhibition: interfacial inhibition
    Laurent Le Corre
    Dominique Padovani
    Scientific Reports, 13
  • [39] Inhibition- and Mechanism-based Inactivation of Human CYP3A4 BY Phyllanthus amarus
    Taesotikul, Theerada
    Somanabandhu, Aimon
    Navinpipatana, Vichien
    Kanjanawart, Sirimas
    Tassaneeyakul, Wongwiwat
    Tassaneeyakul, Wichittra
    DRUG METABOLISM REVIEWS, 2009, 41 : 39 - 39
  • [40] MECHANISM-BASED INHIBITION OF HUMAN-LEUKOCYTE ELASTASE AND CATHEPSIN-G BY SUBSTITUTED DIHYDROURACILS
    GROUTAS, WC
    HUANG, H
    EPP, JB
    VENKATARAMAN, R
    MCCLENAHAN, JJ
    TAGUSAGAWA, F
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1994, 1227 (03): : 130 - 136
12345