Targeting MAPK Signaling Pathway with Cobimetinib (GDC-0973) Enhances Anti-Leukemia Efficacy of Venetoclax (ABT-199/GDC-0199) in Acute Myeloid Leukemia Models

被引:2
|
作者
Han, Lina [1 ]
Zhang, Qi [1 ]
Shi, Ce [2 ]
Cavazos, Antonio [1 ]
Ruvolo, Vivian [1 ]
Leverson, Joel [3 ]
Monique, Dail [4 ]
Phillips, Darren C. [3 ]
Chen, Jun [3 ]
Jin, Sha S. [3 ]
Jacamo, Rodrigo Omar [1 ]
Daver, Naval [1 ]
Jabbour, Elias J. [1 ]
Kantarjian, Hagop M. [1 ]
Andreeff, Michael [1 ]
Sampath, Deepak [4 ]
Konopleva, Marina [1 ]
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Leukemia, Houston, TX USA
[2] Harbin Med Univ, Affiliated Hosp 1, Dept Leukemia, Harbin, Peoples R China
[3] AbbVie Inc, N Chicago, IL USA
[4] Genentech Inc, San Francisco, CA USA
关键词
D O I
10.1182/blood.V128.22.97.97
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
97
引用
收藏
页数:5
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