Residual TP53 Mutation Contributes to Chemoresistance through Clonal Expansion in Acute Myeloid Leukemia

被引：1
|
作者：
Yan, Bowen [1 ]
Chen, Qinwei [1 ]
Xu, Jianfeng [2 ]
Li, Wei [2 ]
Xu, Bing [3 ]
Huang, Suming [4 ]
Qiu, Yi [1 ]
机构：
[1] Univ Florida, Coll Med, Dept Anat & Cell Biol, Gainesville, FL USA
[2] Baylor Coll Med, Dan L Duncan Canc Ctr, Houston, TX 77030 USA
[3] Xiamen Univ, Dept Hematol, Affiliated Hosp 1, Xiamen, Peoples R China
[4] Penn State Univ, Hershey Coll Med, Dept Pediat, Div Hematol & Oncol,Penn State Canc Inst, Hershey, PA USA
来源：
BLOOD | 2019年 / 134卷
关键词：
D O I：
10.1182/blood-2019-127511
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
2731
引用
收藏
页数：3
相关论文
共 50 条
  • [31] TP53 Mutations in Acute Myeloid Leukemia: Still a Daunting Challenge?
    Molica, Matteo
    Mazzone, Carla
    Niscola, Pasquale
    de Fabritiis, Paolo
    FRONTIERS IN ONCOLOGY, 2021, 10
  • [32] Mutant TP53 prevents Telomere Shortening in Acute Myeloid Leukemia
    Wahida, Adam
    Hutter, Stephan
    Gurnari, Carmelo
    Stainczyk, Sabine
    Pagliuca, Simona
    Meggendorfer, Manja
    Laframboise, Thomas
    Haferlach, Claudia
    Kern, Wolfgang
    Westermann, Frank
    Feuerbach, Lars
    Haferlach, Torsten
    Maciejewski, Jaroslaw P.
    BLOOD, 2021, 138
  • [33] Comparison of acute myeloid leukemia and myelodysplastic syndromes with TP53 aberrations
    Sayantanee Dutta
    Jennifer Moritz
    Gudrun Pregartner
    Gerhard G. Thallinger
    Ilona Brandstätter
    Karin Lind
    Simin Rezania
    Freya Lyssy
    Andreas Reinisch
    Armin Zebisch
    Andrea Berghold
    Albert Wölfler
    Heinz Sill
    Annals of Hematology, 2022, 101 : 837 - 846
  • [34] TP53 Mutant Acute Myeloid Leukemia: The Immune and Metabolic Perspective
    Zingarelli, Federico
    Zannoni, Letizia
    Curti, Antonio
    HEMATO, 2022, 3 (04): : 742 - 757
  • [35] THE EXPRESSION OF THE TP53 GENE IN VARIOUS CLASSES OF ACUTE MYELOID LEUKEMIA
    Ahmadzadeh, A.
    Mohammadi, M. Hossein
    Mezginezhad, F.
    Nezhad, H. Aghaee
    Parkhideh, S.
    Khosravi, M.
    Khazaei, Z.
    Adineh, H. A.
    Farsani, M. Allahbakhshian
    WORLD CANCER RESEARCH JOURNAL, 2018, 5 (04)
  • [36] Comparison of acute myeloid leukemia and myelodysplastic syndromes with TP53 aberrations
    Dutta, Sayantanee
    Moritz, Jennifer
    Pregartner, Gudrun
    Thallinger, Gerhard G.
    Brandstaetter, Ilona
    Lind, Karin
    Rezania, Simin
    Lyssy, Freya
    Reinisch, Andreas
    Zebisch, Armin
    Berghold, Andrea
    Woelfler, Albert
    Sill, Heinz
    ANNALS OF HEMATOLOGY, 2022, 101 (04) : 837 - 846
  • [37] Therapeutic Vulnerabilities in Acute Myeloid Leukemia (AML) with <it>TP53</it> Alterations
    Ogunsan, Oluwateniayo
    Antony, Marie
    Noble-Orcutt, Klara
    He, Fiona
    Sachs, Zohar
    FASEB JOURNAL, 2020, 34
  • [38] Clonal evolution in chronic lymphocytic leukemia is associated with an unmutated IGHV status and frequently leads to a combination of loss of TP53 and TP53 mutation
    Bracher, Susanne
    Fuhrmann, Irene
    Jeromin, Sabine
    Nadarajah, Niroshan
    Kern, Wolfgang
    Haferlach, Torsten
    Haferlach, Claudia
    Stengel, Anna
    MOLECULAR BIOLOGY REPORTS, 2022, 49 (12) : 12247 - 12252
  • [39] Clonal evolution in chronic lymphocytic leukemia is associated with an unmutated IGHV status and frequently leads to a combination of loss of TP53 and TP53 mutation
    Susanne Bracher
    Irene Fuhrmann
    Sabine Jeromin
    Niroshan Nadarajah
    Wolfgang Kern
    Torsten Haferlach
    Claudia Haferlach
    Anna Stengel
    Molecular Biology Reports, 2022, 49 : 12247 - 12252
  • [40] Clonal Dynamics and Deterministic Clinical Fate Mapping of Patients with Myelodysplastic Neoplasms and Acute Myeloid Leukemia with TP53 Disruption
    Patel, Shyam Ajay
    Tanenbaum, Benjamin
    Ediriwickrema, Asiri
    Cerny, Jan
    Hutchinson, Lloyd
    Meng, Xiuling
    Gerber, William K.
    Khedr, Salwa
    Selove, William
    Woda, Bruce
    Gerber, Jonathan M.
    BLOOD, 2023, 142
12345